David M. Alvarado, Ph.D.

Affiliations: 
2009 Biology & Biomedical Sciences (Molecular Genetics & Genomics) Washington University, Saint Louis, St. Louis, MO 
Area:
Genetics
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"David Alvarado"

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Michael Lovett grad student 2009 Washington University
 (Genomic approaches for pathway identification in regenerating sensory epithelia of the inner ear.)
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Publications

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Riehl TE, Alvarado D, Ee X, et al. (2020) Hyaluronic acid promotes Lgr5 stem cell proliferation and crypt fission through TLR4 and PGE transactivation of EGFR. American Journal of Physiology. Gastrointestinal and Liver Physiology. 319: G63-G73
Seiler KM, Bajinting A, Alvarado DM, et al. (2020) Patient-derived small intestinal myofibroblasts direct perfused, physiologically responsive capillary development in a microfluidic Gut-on-a-Chip Model. Scientific Reports. 10: 3842
Alvarado DM, Chen B, Iticovici M, et al. (2019) Epithelial IDO1 Modulates AHR and Notch Signaling to Increase Differentiation of Secretory Cells and Alter Mucus-Associated Microbiota. Gastroenterology
Bishnupuri KS, Alvarado DM, Khouri AN, et al. (2019) IDO1 and kynurenine pathway metabolites activate PI3K-Akt signaling in the neoplastic colon epithelium to promote cancer cell proliferation and inhibit apoptosis. Cancer Research
Alvarado DM, Santhanam S, Iticovici M, et al. (2019) 11 EPITHELIAL IDO1 MODULATES AHR AND NOTCH SIGNALING TO ENHANCE SECRETORY CELL DIFFERENTIATION AND ALTERS MUCUS-ASSOCIATED MICROBIOTA Gastroenterology. 156: S84
Alvarado DM, Chen B, Iticovici M, et al. (2019) 422 – Epithelial Ido1 Modulates Ahr and Notch Signaling to Enhance Secretory Cell Differentiation, Augment Mucus Barrier, and Alter Microbiota Gastroenterology. 156: S-82
Riehl TE, Alvarado D, Ee X, et al. (2018) GG protects the intestinal epithelium from radiation injury through release of lipoteichoic acid, macrophage activation and the migration of mesenchymal stem cells. Gut
Alvarado D, Santhanam S, Iticovici M, et al. (2018) P059 Indoleamine 2,3-Dioxygenase 1 Expression Promotes Epithelial Secretory Cell Differentiation Via Aryl Hydrocarbon Receptor Gastroenterology. 154
Santhanam S, Alvarado D, Khouri A, et al. (2017) PD-236 Defining the Signaling Pathways and Functional Role for Kynurenine Metabolites in the Normal and Neoplastic Colon Epithelium Inflammatory Bowel Diseases. 23
Alvarado DM, McCall K, Hecht JT, et al. (2016) Deletions of 5' HOXC genes are associated with lower extremity malformations, including clubfoot and vertical talus. Journal of Medical Genetics. 53: 250-5
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