Said M. Sebti
Affiliations: | University of South Florida, Tampa, FL, United States |
Area:
Biochemistry, Cell BiologyGoogle:
"Said Sebti"Mean distance: (not calculated yet)
Children
Sign in to add trainee| Nichole C. Crespo | grad student | 2001 | University of South Florida |
| Adam E. Carie | grad student | 2008 | University of South Florida |
| Samuel C. Falsetti | grad student | 2008 | University of South Florida |
| Awet G. Tecleab | grad student | 2013 | University of South Florida |
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Publications
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| Kazi A, Ranjan A, Kumar M V V, et al. (2023) Discovery of KRB-456, a KRAS G12D switch-I/II allosteric pocket binder that inhibits the growth of pancreatic cancer patient-derived tumors. Cancer Research Communications |
| Zhou L, Pei X, Zhang Y, et al. (2021) Chk1 inhibition potently blocks STAT3 tyrosine705 phosphorylation, DNA binding activity, and activation of downstream targets in human multiple myeloma cells. Molecular Cancer Research : McR |
| Yang H, Xiang S, Kazi A, et al. (2020) The GTPase KRAS suppresses the P53 tumor suppressor by activating the NRF2-regulated antioxidant defense system in cancer cells. The Journal of Biological Chemistry |
| Sebti SM, Kazi A, Xiang S, et al. (2019) Dual farnesyl and geranylgeranyl transferase inhibitor thwarts mutant KRAS-driven patient-derived pancreatic tumors. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research |
| Kazi A, Xiang S, Yang H, et al. (2019) Abstract 3088: Farnesyl/geranylgeranyl transferase dual inhibitor thwarts mutant KRas-driven patient-derived pancreatic tumors Cancer Research |
| Vangipurapu R, Chen L, Kennedy P, et al. (2018) Abstract 1669: Identification of mutant KRas-Raf-1 binding disruptors Cancer Research. 78: 1669-1669 |
| Kuchay S, Giorgi C, Simoneschi D, et al. (2017) PTEN counteracts FBXL2 to promote IP3R3- and Ca(2+)-mediated apoptosis limiting tumour growth. Nature |
| Nishimura S, Mishra-Gorur K, Park J, et al. (2017) Combined HMG-COA reductase and prenylation inhibition in treatment of CCM. Proceedings of the National Academy of Sciences of the United States of America |
| Husain K, Centeno BA, Coppola D, et al. (2017) d-Tocotrienol, a natural form of vitamin E, inhibits pancreatic cancer stem-like cells and prevents pancreatic cancer metastasis. Oncotarget |
| Betts BC, Veerapathran A, Pidala J, et al. (2017) Targeting Aurora kinase A and JAK2 prevents GVHD while maintaining Treg and antitumor CTL function. Science Translational Medicine. 9 |