Don X. Nguyen, Ph.D.

Affiliations: 
2004 University of Rochester, Rochester, NY 
Area:
Molecular Biology, Cell Biology
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"Don Nguyen"

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Dennis J. McCance grad student 2004 Rochester
 (Specific functions of the retinoblastoma tumor suppressor protein required for cellular differentiation.)
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Publications

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Cai WL, Chen JF, Chen H, et al. (2022) Human WDR5 promotes breast cancer growth and metastasis via KMT2-independent translation regulation. Elife. 11
Arnal-Estapé A, Cai WL, Albert AE, et al. (2020) Tumor progression and chromatin landscape of lung cancer are regulated by the lineage factor GATA6. Oncogene
Haskins JW, Nguyen DX, Stern DF. (2014) Neuregulin 1-activated ERBB4 interacts with YAP to induce Hippo pathway target genes and promote cell migration. Science Signaling. 7: ra116
Karlin KL, Mondal G, Hartman JK, et al. (2014) The oncogenic STP axis promotes triple-negative breast cancer via degradation of the REST tumor suppressor. Cell Reports. 9: 1318-32
Colavito SA, Zou MR, Yan Q, et al. (2014) Significance of glioma-associated oncogene homolog 1 (GLI1) expression in claudin-low breast cancer and crosstalk with the nuclear factor kappa-light-chain-enhancer of activated B cells (NFκB) pathway. Breast Cancer Research : Bcr. 16: 444
Cheung WK, Zhao M, Liu Z, et al. (2013) Control of alveolar differentiation by the lineage transcription factors GATA6 and HOPX inhibits lung adenocarcinoma metastasis. Cancer Cell. 23: 725-38
Sun T, Aceto N, Meerbrey KL, et al. (2011) Activation of multiple proto-oncogenic tyrosine kinases in breast cancer via loss of the PTPN12 phosphatase. Cell. 144: 703-18
Nguyen DX, McCance DJ. (2005) Role of the retinoblastoma tumor suppressor protein in cellular differentiation. Journal of Cellular Biochemistry. 94: 870-9
Nguyen DX, Baglia LA, Huang SM, et al. (2004) Acetylation regulates the differentiation-specific functions of the retinoblastoma protein. The Embo Journal. 23: 1609-18
Westbrook TF, Nguyen DX, Thrash BR, et al. (2002) E7 abolishes raf-induced arrest via mislocalization of p21(Cip1). Molecular and Cellular Biology. 22: 7041-52
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