Sanda I. Despa, Ph.D.

Affiliations: 
2000 Limburgs Universitair Centrum (Belgium) 
Area:
Animal Physiology Biology, Medical Biophysics, Cell Biology
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Paul Steels grad student 2000 Limburgs Universitair Centrum (Belgium)
 (Microfluorimetry of epithelial cells: Lifetime-based sensing of sodium(+) concentration and the effects of chemical hypoxia.)
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Publications

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Velmurugan S, Liu T, Chen KC, et al. (2023) Distinct Effects of Mitochondrial Na/Ca Exchanger Inhibition and Ca Uniporter Activation on Ca Sparks and Arrhythmogenesis in Diabetic Rats. Journal of the American Heart Association. e029997
Verma N, Liu M, Ly H, et al. (2019) Diabetic microcirculatory disturbances and pathologic erythropoiesis are provoked by deposition of amyloid-forming amylin in red blood cells and capillaries. Kidney International
Velmurugan S, Hoskins A, Despa F, et al. (2019) Abstract 766: SGLT-Mediated Na + Overload Results in Oxidative Stress and Abnormal SR Ca 2+ Release in Diabetic Hearts Circulation Research. 125
Popescu I, Yin G, Velmurugan S, et al. (2018) Lower sarcoplasmic reticulum Ca threshold for triggering afterdepolarizations in diabetic rat hearts. Heart Rhythm
Despa S. (2018) Myocyte [Na+]i Dysregulation in Heart Failure and Diabetic Cardiomyopathy Frontiers in Physiology. 9: 1303
Stewart BD, Scott CE, McCoy TP, et al. (2018) Computational modeling of amylin-induced calcium dysregulation in rat ventricular cardiomyocytes. Cell Calcium. 71: 65-74
Hoskins A, Verma N, Despa F, et al. (2018) Activation of Ca2+-dependent signaling causes postpartum cardiac hypertrophy in rats with gestational diabetes Journal of Molecular and Cellular Cardiology. 124: 92
Liu M, Hoskins A, Verma N, et al. (2017) Amylin and diabetic cardiomyopathy - amylin-induced sarcolemmal Ca(2+) leak is independent of diabetic remodeling of myocardium. Biochimica Et Biophysica Acta
Van Steenbergen A, Balteau M, Ginion A, et al. (2017) Sodium-myoinositol cotransporter-1, SMIT1, mediates the production of reactive oxygen species induced by hyperglycemia in the heart. Scientific Reports. 7: 41166
Liao Z, Ginsburg KS, Bartos DC, et al. (2017) High Diastolic Sodium Influx in Heart Failure has Drug-Sensitivities Like Late Sodium Current, but Produces Inward Current at Diastolic Potentials Biophysical Journal. 112: 333a
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