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Jianke Zhang

Affiliations: 
Immunology and Microbial Pathogenesis Thomas Jefferson University, Philadelphia, PA, United States 
Area:
Microbiology Biology, Immunology, Cell Biology
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"Jianke Zhang"
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Stephen M. Rosenberg grad student 2010 Thomas Jefferson
Josephine F. Wixted grad student 2012 Thomas Jefferson

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Publications

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Zhang X, Dowling JP, Zhang J. (2019) RIPK1 can mediate apoptosis in addition to necroptosis during embryonic development. Cell Death & Disease. 10: 245
Dowling JP, Alsabbagh M, Del Casale C, et al. (2019) TRADD regulates perinatal development and adulthood survival in mice lacking RIPK1 and RIPK3. Nature Communications. 10: 705
Chen D, Tong J, Yang L, et al. (2018) PUMA amplifies necroptosis signaling by activating cytosolic DNA sensors. Proceedings of the National Academy of Sciences of the United States of America
Li J, Qian L, Dowling JP, et al. (2017) Daxx plays a novel role in T cell survival but is dispensable in Fas-induced apoptosis. Plos One. 12: e0174011
Dowling JP, Cai Y, Bertin J, et al. (2016) Kinase-independent function of RIP1, critical for mature T-cell survival and proliferation. Cell Death & Disease. 7: e2379
Zhang X, Fan C, Zhang H, et al. (2016) MLKL and FADD Are Critical for Suppressing Progressive Lymphoproliferative Disease and Activating the NLRP3 Inflammasome. Cell Reports
Legarda D, Justus SJ, Ang RL, et al. (2016) CYLD Proteolysis Protects Macrophages from TNF-Mediated Auto-necroptosis Induced by LPS and Licensed by Type I IFN. Cell Reports
Kang S, Fernandes-Alnemri T, Rogers C, et al. (2015) Caspase-8 scaffolding function and MLKL regulate NLRP3 inflammasome activation downstream of TLR3. Nature Communications. 6: 7515
Dowling JP, Nair A, Zhang J. (2015) A novel function of RIP1 in postnatal development and immune homeostasis by protecting against RIP3-dependent necroptosis and FADD-mediated apoptosis. Frontiers in Cell and Developmental Biology. 3: 12
Volk A, Li J, Xin J, et al. (2014) Co-inhibition of NF-κB and JNK is synergistic in TNF-expressing human AML. The Journal of Experimental Medicine. 211: 1093-108
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