Jay S. Desgrosellier, Ph.D.
Affiliations: | 2004 | Vanderbilt University, Nashville, TN |
Area:
Pharmacology, Animal Physiology BiologyGoogle:
"Jay Desgrosellier"Mean distance: (not calculated yet)
Parents
Sign in to add mentor| Joey Barnett | grad student | 2004 | Vanderbilt | |
| (The role of type I TGFbeta receptors in epithelial-mesenchymal transformation in the atrioventricular cushion.) | ||||
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Publications
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| Sun Q, Wang Y, Officer A, et al. (2020) Abstract 6024: An integrin αvβ3+ stem-like tumor cell subset promotes breast cancer progression via c-Jun/AXL signaling Cancer Research. 80: 6024-6024 |
| Sun Q, Wang Y, Desgrosellier JS. (2019) Combined Bcl-2/Src inhibition synergize to deplete stem-like breast cancer cells. Cancer Letters |
| Sun Q, Lesperance J, Wettersten H, et al. (2018) Proapoptotic PUMA targets stem-like breast cancer cells to suppress metastasis. The Journal of Clinical Investigation. 128: 531-544 |
| Seguin L, Camargo MF, Wettersten HI, et al. (2017) Galectin-3, a druggable vulnerability for KRAS-addicted cancers. Cancer Discovery |
| Sun Q, Lesperance J, Desgrosellier JS. (2016) Abstract 3321: PUMA expression targets αvβ3/Slug+ “stem-like” tumor cells to prevent breast cancer progression independent of subtype Cancer Research. 76: 3321-3321 |
| Seguin L, Desgrosellier JS, Weis SM, et al. (2015) Integrins and cancer: regulators of cancer stemness, metastasis, and drug resistance. Trends in Cell Biology. 25: 234-40 |
| Desgrosellier JS, Lesperance J, Seguin L, et al. (2014) Integrin αvβ3 drives slug activation and stemness in the pregnant and neoplastic mammary gland. Developmental Cell. 30: 295-308 |
| Seguin L, Kato S, Franovic A, et al. (2014) An integrin β₃-KRAS-RalB complex drives tumour stemness and resistance to EGFR inhibition. Nature Cell Biology. 16: 457-68 |
| Kato S, Seguin L, Franovic A, et al. (2014) Abstract 4240: Targeting Galectin-3 to reverse tumor stemness and drug resistance Cancer Research. 74: 4240-4240 |
| Desgrosellier JS, Lesperance J, Seguin L, et al. (2014) Abstract 3034: Integrin αvβ3 drives Slug activation and stemness in the pregnant and neoplastic mammary gland Cancer Research. 74: 3034-3034 |