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Yu-Hsiu Wang, Ph.D.

Affiliations: 
2002-2007 Chemistry/Life Science National Taiwan Univeersity, Taipei, Taipei City, Taiwan 
 2008-2013 Chemistry/Institute for Medicine and Engineering University of Pennsylvania, Philadelphia, PA, United States 
 2014- Mechanobiology Institute National University of Singapore, Singapore, Singapore 
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Parents

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Pi-Tai Chou research assistant 2004-2007 National Taiwan University
Paul A. Janmey grad student 2008-2013 Penn
 (Divalent cation- and cholesterol-induced perturbation in PIP 2 lateral organization in model membranes - Cluster formation, phase partitioning, and PIP2-protein interactions.)
Michael P. Sheetz post-doc 2014- National University of Singapore
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Publications

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Wang YH, Sheetz MP. (2022) Transcription-independent functions of p53 in DNA repair pathway selection. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. e2200122
Wang YH, Sheetz MP. (2022) When PIP Meets p53: Nuclear Phosphoinositide Signaling in the DNA Damage Response. Frontiers in Cell and Developmental Biology. 10: 903994
Wang YH, Ho TLF, Hariharan A, et al. (2022) Rapid recruitment of p53 to DNA damage sites directs DNA repair choice and integrity. Proceedings of the National Academy of Sciences of the United States of America. 119: e2113233119
Tijore A, Yao M, Wang YH, et al. (2021) Selective killing of transformed cells by mechanical stretch. Biomaterials. 275: 120866
Cruz K, Wang YH, Oake SA, et al. (2021) Polyelectrolyte Gels Formed by Filamentous Biopolymers: Dependence of Crosslinking Efficiency on the Chemical Softness of Divalent Cations. Gels (Basel, Switzerland). 7
Bucki R, Wang YH, Yang C, et al. (2019) Lateral distribution of phosphatidylinositol 4,5-bisphosphate in membranes regulates formin and ARP2/3 -mediated actin nucleation. The Journal of Biological Chemistry
Wang Y, Hariharan A, Bastianello G, et al. (2018) IPMK and PTEN Regulate Nuclear Phosphoinositide-Dependent ATR Signaling upon DNA Damage Biophysical Journal. 114: 82a
Wang YH, Hariharan A, Bastianello G, et al. (2017) DNA damage causes rapid accumulation of phosphoinositides for ATR signaling. Nature Communications. 8: 2118
Wang YH, Bucki R, Janmey PA. (2016) Cholesterol-dependent Phase-demixing in Lipid Bilayers as a Switch for the Activity of the Phosphoinositide-binding Cytoskeletal Protein Gelsolin. Biochemistry
Chou SW, Liu CL, Liu TM, et al. (2016) Infrared-active quadruple contrast FePt nanoparticles for multiple scale molecular imaging. Biomaterials. 85: 54-64
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