Amy E. Coon, Ph.D.
Affiliations: | 2006 | University of Arizona, Tucson, AZ |
Area:
Molecular Biology, Oncology, Cell BiologyGoogle:
"Amy Coon"Mean distance: (not calculated yet)
Parents
Sign in to add mentor| Garth Powis | grad student | 2006 | University of Arizona | |
| (Analysis of antioxidant responsive gene expression changes by thioredoxin system inhibitors and hypoxia.) | ||||
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| Kim YH, Coon A, Baker AF, et al. (2011) Antitumor agent PX-12 inhibits HIF-1α protein levels through an Nrf2/PMF-1-mediated increase in spermidine/spermine acetyl transferase. Cancer Chemotherapy and Pharmacology. 68: 405-13 |
| Snodgrass RG, Collier AC, Coon AE, et al. (2010) Mitomycin C inhibits ribosomal RNA: a novel cytotoxic mechanism for bioreductive drugs. The Journal of Biological Chemistry. 285: 19068-75 |
| Baker AF, Landowski T, Dorr R, et al. (2007) The antitumor agent imexon activates antioxidant gene expression: evidence for an oxidative stress response. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 13: 3388-94 |
| Meuillet EJ, Ihle N, Baker AF, et al. (2004) In vivo molecular pharmacology and antitumor activity of the targeted Akt inhibitor PX-316. Oncology Research. 14: 513-27 |
| Meuillet EJ, Mahadevan D, Berggren M, et al. (2004) Thioredoxin-1 binds to the C2 domain of PTEN inhibiting PTEN's lipid phosphatase activity and membrane binding: a mechanism for the functional loss of PTEN's tumor suppressor activity. Archives of Biochemistry and Biophysics. 429: 123-33 |
| Meuillet EJ, Mahadevan D, Vankayalapati H, et al. (2003) Specific inhibition of the Akt1 pleckstrin homology domain by D-3-deoxy-phosphatidyl-myo-inositol analogues. Molecular Cancer Therapeutics. 2: 389-99 |
| Powis G, Mustacich D, Coon A. (2000) The role of the redox protein thioredoxin in cell growth and cancer. Free Radical Biology & Medicine. 29: 312-22 |