Ivone G. Bruno, Ph.D.

Affiliations: 
2004 The University of Texas Graduate School of Biomedical Sciences at Houston 
Area:
Biomedical Engineering, Molecular Biology
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"Ivone Bruno"

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Gilbert J. Cote grad student 2004 The University of Texas Graduate School of Biomedical Sciences at Houston
 (Correction of aberrant FGFR1 RNA splicing through blocking intronic regulatory elements.)
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Publications

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Gao X, Yi Y, Lv J, et al. (2023) Low RNA stability signifies strong expression regulatability of tumor suppressors. Nucleic Acids Research
Li Y, Yi Y, Lv J, et al. (2023) Low RNA stability signifies increased post-transcriptional regulation of cell identity genes. Nucleic Acids Research
Li Y, Zhou G, Bruno IG, et al. (2019) Transient introduction of human telomerase mRNA improves hallmarks of progeria cells. Aging Cell. e12979
Bruno IG, Karam R, Huang L, et al. (2011) Identification of a microRNA that activates gene expression by repressing nonsense-mediated RNA decay. Molecular Cell. 42: 500-10
Karam R, Carvalho J, Bruno I, et al. (2008) The NMD mRNA surveillance pathway downregulates aberrant E-cadherin transcripts in gastric cancer cells and in CDH1 mutation carriers. Oncogene. 27: 4255-60
Bruno IG, Jin W, Cote GJ. (2004) Correction of aberrant FGFR1 alternative RNA splicing through targeting of intronic regulatory elements. Human Molecular Genetics. 13: 2409-20
Jin W, Bruno IG, Xie TX, et al. (2003) Polypyrimidine tract-binding protein down-regulates fibroblast growth factor receptor 1 alpha-exon inclusion. Cancer Research. 63: 6154-7
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