Patrick M. Brauer, Ph.D.

Affiliations: 
2010 University of Illinois at Chicago, Health Sciences Center, Chicago, IL 60612, United States 
Area:
Biochemistry, Molecular Biology, Cell Biology
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Angela Tyner grad student 2010 University of Illinois at Chicago, Health Sciences Center
 (Growth regulation of prostate cancer by the intracellular protein tyrosine kinase 6.)
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Publications

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Dominguez-Brauer C, Hao Z, Elia AJ, et al. (2016) Mule Regulates the Intestinal Stem Cell Niche via the Wnt Pathway and Targets EphB3 for Proteasomal and Lysosomal Degradation. Cell Stem Cell
Zheng Y, Wang Z, Bie W, et al. (2013) PTK6 activation at the membrane regulates epithelial-mesenchymal transition in prostate cancer. Cancer Research. 73: 5426-37
Brauer PM, Zheng Y, Evans MD, et al. (2011) The alternative splice variant of protein tyrosine kinase 6 negatively regulates growth and enhances PTK6-mediated inhibition of β-catenin. Plos One. 6: e14789
Brauer PM, Zheng Y, Wang L, et al. (2010) Cytoplasmic retention of protein tyrosine kinase 6 promotes growth of prostate tumor cells. Cell Cycle (Georgetown, Tex.). 9: 4190-9
Brauer PM, Tyner AL. (2010) Building a better understanding of the intracellular tyrosine kinase PTK6 - BRK by BRK. Biochimica Et Biophysica Acta. 1806: 66-73
Palka-Hamblin HL, Gierut JJ, Bie W, et al. (2010) Identification of beta-catenin as a target of the intracellular tyrosine kinase PTK6. Journal of Cell Science. 123: 236-45
Dominguez-Brauer C, Brauer PM, Chen YJ, et al. (2010) Tumor suppression by ARF: gatekeeper and caretaker. Cell Cycle (Georgetown, Tex.). 9: 86-9
Brauer PM, Tyner AL. (2009) RAKing in AKT: a tumor suppressor function for the intracellular tyrosine kinase FRK. Cell Cycle (Georgetown, Tex.). 8: 2728-32
Dominguez-Brauer C, Chen YJ, Brauer PM, et al. (2009) ARF stimulates XPC to trigger nucleotide excision repair by regulating the repressor complex of E2F4. Embo Reports. 10: 1036-42
PALKAHAMBLIN H, GIERUT J, BRAUER P, et al. (2008) M1646 The Intracellular Tyrosine Kinase PTK6 Phosphorylates Beta-Catenin and Negatively Regulates Beta-Catenin/Tcf Transcription Gastroenterology. 134: A-389-A-389
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