Allison M. Pledgie, Ph.D.

Affiliations: 
2006 Johns Hopkins University, Baltimore, MD 
Area:
Molecular Biology
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"Allison Pledgie"
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Nancy Davidson grad student 2006 Johns Hopkins
 (The molecular pathways of polyamine catabolism in human breast cancer cell lines.)
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Huang Y, Keen JC, Pledgie A, et al. (2006) Polyamine analogues down-regulate estrogen receptor alpha expression in human breast cancer cells. The Journal of Biological Chemistry. 281: 19055-63
Pledgie A, Huang Y, Hacker A, et al. (2005) Spermine oxidase SMO(PAOh1), not N1-acetylpolyamine oxidase PAO, is the primary source of Cytotoxic H2O2 in polyamine analogue-treated human breast cancer cell lines Journal of Biological Chemistry. 280: 39843-39851
Huang Y, Pledgie A, Rubin E, et al. (2005) Role of p53/p21Waf1/Cip1 in the regulation of polyamine analogue-induced growth inhibition and cell death in human breast cancer cells Cancer Biology and Therapy. 4: 1006-1013
Huang Y, Pledgie A, Casero RA, et al. (2005) Molecular mechanisms of polyamine analogs in cancer cells. Anti-Cancer Drugs. 16: 229-41
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