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Andrea G. Cochran

Affiliations: 
1996- Genentech, Inc., San Francisco, CA, United States 
Area:
proteins, biophysics, biochemistry
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"Andrea Cochran"
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Parents

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Peter G. Schultz grad student 1986-1991 UC Berkeley
Peter S. Kim post-doc 1992-1996 Whitehead Institute for Biomedical Research (MIT)

Children

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E Megan Flynn research assistant Genentech, Inc.
Oscar Huang research assistant Genentech, Inc.
Stephen Russell research assistant Genentech, Inc.
Eric Bourhis grad student Genentech, Inc.
Frederic Fellouse grad student Genentech, Inc.
Matthew L. Bentley post-doc Genentech, Inc.
Miro Brajenovic post-doc Genentech, Inc.
Tania N. Gonzalez post-doc Genentech, Inc. (Cell Biology Tree)
Joanne D. Kotz post-doc Genentech, Inc.
Mariano Oppikofer post-doc Genentech, Inc.
Tatjana Petojevic post-doc Genentech, Inc.
Asad Taherbhoy post-doc Genentech, Inc. (Cell Biology Tree)
Dieu An H Nguyen post-doc 2022- Genentech, Inc. (Cell Biology Tree)

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Publications

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Cochran AG, Flynn M. (2023) GNE-235: A Lead Compound Selective for the Second Bromodomain of PBRM1. Journal of Medicinal Chemistry
Miller GM, Flynn EM, Tom J, et al. (2022) Trifluoroacetyl Lysine as a Bromodomain Binding Mimic of Lysine Acetylation. Acs Chemical Biology
Cochran AG, Conery AR, Sims RJ. (2019) Bromodomains: a new target class for drug development. Nature Reviews. Drug Discovery
Wang S, Tsui V, Crawford TD, et al. (2018) GNE-371, a Potent and Selective Chemical Probe for the Second Bromodomains of Human Transcription-Initiation-Factor TFIID Subunit 1 and Transcription-Initiation-Factor TFIID Subunit 1-like. Journal of Medicinal Chemistry
Oppikofer M, Sagolla M, Haley B, et al. (2017) Non-canonical reader modules of BAZ1A promote recovery from DNA damage. Nature Communications. 8: 862
Oppikofer M, Bai T, Gan Y, et al. (2017) Expansion of the ISWI chromatin remodeler family with new active complexes. Embo Reports
Crawford TD, Audia JE, Bellon S, et al. (2017) GNE-886: A Potent and Selective Inhibitor of the Cat Eye Syndrome Chromosome Region Candidate 2 Bromodomain (CECR2). Acs Medicinal Chemistry Letters. 8: 737-741
Crawford TD, Vartanian S, Côté A, et al. (2017) Inhibition of bromodomain-containing protein 9 for the prevention of epigenetically-defined drug resistance. Bioorganic & Medicinal Chemistry Letters
Crawford TD, Romero FA, Lai KW, et al. (2016) Discovery of a Potent and Selective in Vivo Probe (GNE-272) for the Bromodomains of CBP/EP300. Journal of Medicinal Chemistry
Crawford TD, Tsui V, Flynn EM, et al. (2016) Diving into the water: Inducible binding conformations for BRD4, TAF1(2), BRD9, and CECR2 bromodomains. Journal of Medicinal Chemistry
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