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Bruno Calabretta

Affiliations: 
Molecular Pharmacology and Structural Biology Thomas Jefferson University, Philadelphia, PA, United States 
Area:
Cell Biology, Biochemistry, Molecular Biology, Oncology
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"Bruno Calabretta"
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Todd J. Waldron grad student 2010 Thomas Jefferson
Aubrey Watkins grad student 2012 Thomas Jefferson

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Publications

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Porazzi P, Petruk S, Pagliaroli L, et al. (2021) Targeting chemotherapy to de-condensed H3K27me3-marked chromatin of AML cells enhances leukemia suppression. Cancer Research
Silvestri G, Trotta R, Stramucci L, et al. (2020) Persistence of Drug-Resistant Leukemic Stem Cells and Impaired NK Cell Immunity in CML Patients Depend on Antiproliferative and PP2A-Activating Functions. Blood Cancer Discovery. 1: 48-67
De Dominici M, Porazzi P, Xiao Y, et al. (2020) Selective inhibition of Ph-positive ALL cell growth through kinase-dependent and independent effects by CDK6-specific PROTACs. Blood
Spagnuolo M, Regazzo G, Sacconi A, et al. (2020) Abstract 2538: Investigating the role of the oncogenic miR-17-92 cluster as involved in TKI-resistance enhancing the survival of MYB-dependent Ph+ acute lymphoblastic leukemia cells Cancer Research. 80: 2538-2538
Kasner MT, Wilde L, Keiffer G, et al. (2019) A phase I trial of palbociclib in combination with dexamethasone in relapsed or refractory adult B-cell acute lymphoblastic leukemia (ALL). Journal of Clinical Oncology. 37
Silvestri G, Trotta R, Stramucci L, et al. (2019) A 14q32.31 Genomic-Imprinted DLK1-DIO3 microrna promotes Leukemogenesis By Inducing Stem Cell Quiescence and Inhibiting NK Cell Anti-Cancer Immunity Blood. 134: 4141-4141
Minieri V, De Dominici M, Porazzi P, et al. (2018) Targeting STAT5 or STAT5-regulated pathways suppresses leukemogenesis of Ph+ acute lymphoblastic leukemia. Cancer Research
Spagnuolo M, Regazzo G, De Dominici M, et al. (2018) Transcriptional activation of the miR-17-92 cluster is involved in the growth-promoting effects of MYB in human Ph-positive leukemia cells. Haematologica
Barbieri E, Trizzino M, Welsh SA, et al. (2018) Targeted Enhancer Activation by a Subunit of the Integrator Complex. Molecular Cell. 71: 103-116.e7
Parenti S, Montorsi L, Fantini S, et al. (2018) KLF4 mediates the effect of 5-ASA on the β-catenin pathway in colon cancer cells. Cancer Prevention Research (Philadelphia, Pa.)
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