Lucas B. Sullivan, Ph.D.

Affiliations: 
2013 Integrated Graduate Program in the Life Sciences Northwestern University, Evanston, IL 
Area:
Cell Biology, Biochemistry, Medicine and Surgery
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Navdeep S. Chandel grad student 2013 Northwestern
 (The proto-oncometabolite fumarate binds glutathione to amplify reactive oxygen species dependent signaling.)
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Publications

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Uo T, Ojo KK, Sprenger CCT, et al. (2024) A Compound that Inhibits Glycolysis in Prostate Cancer Controls Growth of Advanced Prostate Cancer. Molecular Cancer Therapeutics
Hart ML, Quon E, Vigil ABG, et al. (2023) Mitochondrial redox adaptations enable alternative aspartate synthesis in SDH-deficient cells. Elife. 12
Li Z, Ji BW, Dixit PD, et al. (2022) Cancer cells depend on environmental lipids for proliferation when electron acceptors are limited. Nature Metabolism
Arnold PK, Jackson BT, Paras KI, et al. (2022) A non-canonical tricarboxylic acid cycle underlies cellular identity. Nature. 603: 477-481
Rossmann MP, Hoi K, Chan V, et al. (2021) Cell-specific transcriptional control of mitochondrial metabolism by TIF1γ drives erythropoiesis. Science (New York, N.Y.). 372: 716-721
Keibler MA, Dong W, Korthauer KD, et al. (2021) Differential Substrate Use in EGF- and Oncogenic KRAS-Stimulated Human Mammary Epithelial Cells. The Febs Journal
Luengo A, Li Z, Gui DY, et al. (2020) Increased demand for NAD relative to ATP drives aerobic glycolysis. Molecular Cell
Davidsen K, Sullivan LB. (2020) Free Asparagine or Die: Cancer Cells Require Proteasomal Protein Breakdown to Survive Asparagine Depletion. Cancer Discovery. 10: 1632-1634
Li Y, Ivica NA, Dong T, et al. (2020) MFSD7C switches mitochondrial ATP synthesis to thermogenesis in response to heme. Nature Communications. 11: 4837
Augert A, Mathsyaraja H, Ibrahim AH, et al. (2020) MAX Functions as a Tumor Suppressor and Rewires Metabolism in Small Cell Lung Cancer. Cancer Cell
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