Lorenzo Federico, Ph.D.

Affiliations: 
2011 University of Kentucky, Lexington, KY 
Area:
Cell Biology
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"Lorenzo Federico"
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Susan S. Smyth grad student 2011 University of Kentucky
 (Studies on the regulation of Brown adipogenesis and obesity by autotaxin and lysophosphatidic acid signaling.)
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Publications

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Mitchell KG, Diao L, Karpinets T, et al. (2020) Neutrophil expansion defines an immunoinhibitory peripheral and intratumoral inflammatory milieu in resected non-small cell lung cancer: a descriptive analysis of a prospectively immunoprofiled cohort. Journal For Immunotherapy of Cancer. 8
Wang Z, Sun K, Xiao Y, et al. (2019) Niraparib activates interferon signaling and potentiates anti-PD-1 antibody efficacy in tumor models. Scientific Reports. 9: 1853
Mitchell KG, Diao L, Tran HT, et al. (2019) Association of relative neutrophilia with a distinct immunoinhibitory milieu in non-small cell lung cancer. Journal of Clinical Oncology. 37: e14047-e14047
Negrao MV, Karpinets T, Li J, et al. (2019) Abstract 1176: Immunogenomic profiling identifies a subgroup of squamous cell lung cancers with immunosuppressed tumor microenvironment and correlates TGF-beta and Wnt/beta-catenin signaling as predictive of low PD-L1 expression Cancer Research. 79: 1176-1176
Federico L, Yang L, Brandon J, et al. (2018) Lipid phosphate phosphatase 3 regulates adipocyte sphingolipid synthesis, but not developmental adipogenesis or diet-induced obesity in mice. Plos One. 13: e0198063
McGrail DJ, Federico L, Li Y, et al. (2018) Multi-omics analysis reveals neoantigen-independent immune cell infiltration in copy-number driven cancers. Nature Communications. 9: 1317
Federico L, Haymaker CL, Forget M, et al. (2018) A preclinical study of tumor-infiltrating lymphocytes in NSCLC. Journal of Clinical Oncology. 36: 161-161
Sepesi B, Federico L, Mitchell K, et al. (2018) P1.03-12 PD-L1 Expression is Predominant in CD68+ Tumor-Associated Macrophages in Stage I-III Non-Small Cell Lung Cancers Journal of Thoracic Oncology. 13: S516
Federico L, Chong Z, Zhang D, et al. (2017) A murine preclinical syngeneic transplantation model for breast cancer precision medicine. Science Advances. 3: e1600957
Peters HL, Tripathi SC, Kerros C, et al. (2017) Serine Proteases Enhance Immunogenic Antigen Presentation on Lung Cancer Cells. Cancer Immunology Research
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