Ian F. Pitha-Rowe, Ph.D.

Affiliations: 
2004 Dartmouth College, Hanover, NH, United States 
Area:
Molecular Biology
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Ethan Dmitrovsky grad student 2004 Dartmouth
 (Post-translational modification in retinoid action: A role for UBE1L in cancer therapy and chemoprevention.)
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Publications

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Shah SJ, Blumen S, Pitha-Rowe I, et al. (2008) UBE1L represses PML/RAR{alpha} by targeting the PML domain for ISG15ylation. Molecular Cancer Therapeutics. 7: 905-14
Ma Y, Feng Q, Pitha-Rowe I, et al. (2007) Gene profiling uncovers retinoid target genes. Methods in Molecular Biology (Clifton, N.J.). 383: 101-21
Pitha-Rowe IF, Pitha PM. (2007) Viral defense, carcinogenesis and ISG15: novel roles for an old ISG. Cytokine & Growth Factor Reviews. 18: 409-17
Pitha-Rowe I, Petty WJ, Feng Q, et al. (2004) Microarray analyses uncover UBE1L as a candidate target gene for lung cancer chemoprevention. Cancer Research. 64: 8109-15
Dragnev KH, Pitha-Rowe I, Ma Y, et al. (2004) Specific chemopreventive agents trigger proteasomal degradation of G1 cyclins: implications for combination therapy. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 10: 2570-7
Sempere LF, Freemantle S, Pitha-Rowe I, et al. (2004) Expression profiling of mammalian microRNAs uncovers a subset of brain-expressed microRNAs with possible roles in murine and human neuronal differentiation. Genome Biology. 5: R13
Pitha-Rowe I, Hassel BA, Dmitrovsky E. (2004) Involvement of UBE1L in ISG15 conjugation during retinoid-induced differentiation of acute promyelocytic leukemia. The Journal of Biological Chemistry. 279: 18178-87
Pitha-Rowe I, Petty WJ, Kitareewan S, et al. (2003) Retinoid target genes in acute promyelocytic leukemia. Leukemia. 17: 1723-30
Kitareewan S, Pitha-Rowe I, Sekula D, et al. (2002) UBE1L is a retinoid target that triggers PML/RARalpha degradation and apoptosis in acute promyelocytic leukemia. Proceedings of the National Academy of Sciences of the United States of America. 99: 3806-11
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