Robert A. Casero, Jr.
Affiliations: | 1984- | Johns Hopkins University, Baltimore, MD |
Area:
Molecular Biology, Genetics, Cell BiologyWebsite:
https://www.hopkinsmedicine.org/profiles/details/robert-caseroGoogle:
"Robert Anthony Casero" OR "Robert A. Casero Jr."Parents
Sign in to add mentor| Carl W Porter | grad student | 1984 | SUNY Buffalo | |
| (Biological and biochemical characterization of spermine involvement in cell proliferation) | ||||
Children
Sign in to add trainee| Christin L. Hanigan | grad student | 2008 | Johns Hopkins |
| Tiffany Dunston | post-doc | 2017- | Johns Hopkins Medical School (Chemistry Tree) |
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Publications
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| Steimbach RR, Herbst-Gervasoni CJ, Lechner S, et al. (2022) Aza-SAHA Derivatives Are Selective Histone Deacetylase 10 Chemical Probes That Inhibit Polyamine Deacetylation and Phenocopy HDAC10 Knockout. Journal of the American Chemical Society |
| Stewart TM, Foley JR, Holbert CE, et al. (2022) Histone deacetylase 10 liberates spermidine to support polyamine homeostasis and tumor cell growth. The Journal of Biological Chemistry. 102407 |
| Al-Hamashi AA, Koranne R, Dlamini S, et al. (2021) A new class of cytotoxic agents targets tubulin and disrupts microtubule dynamics. Bioorganic Chemistry. 116: 105297 |
| Holbert CE, Dunworth M, Foley JR, et al. (2020) Autophagy induction by exogenous polyamines is an artifact of bovine serum amine oxidase activity in culture serum. The Journal of Biological Chemistry. 295: 9061-9068 |
| Holbert CE, Dunworth M, Foley JR, et al. (2020) Autophagy induction by exogenous polyamines is an artifact of bovine serum amine oxidase activity in culture serum. The Journal of Biological Chemistry |
| Murray Stewart T, Khomutov M, Foley JR, et al. (2020) (R,R)-1,12-Dimethylspermine can mitigate abnormal spermidine accumulation in Snyder-Robinson syndrome. The Journal of Biological Chemistry |
| Murray-Stewart T, Dunworth M, Foley JR, et al. (2018) Polyamine Homeostasis in Snyder-Robinson Syndrome. Medical Sciences (Basel, Switzerland). 6 |
| Murray Stewart T, Dunston TT, Woster PM, et al. (2018) Polyamine catabolism and oxidative damage. The Journal of Biological Chemistry |
| Murray-Stewart T, Dunworth M, Lui Y, et al. (2018) Curcumin mediates polyamine metabolism and sensitizes gastrointestinal cancer cells to antitumor polyamine-targeted therapies. Plos One. 13: e0202677 |
| Almaliti J, Al-Hamashi AA, Negmeldin AT, et al. (2016) Largazole Analogues Embodying Radical Changes in the Depsipeptide Ring: Development of a More Selective and Highly Potent Analogue. Journal of Medicinal Chemistry |