Alex Franzusoff

Affiliations: 
University of Colorado Anschutz Medical Campus, Denver, Aurora, CO 
Area:
Cell Biology, Immunology
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"Alex Franzusoff"
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Publications

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Puig-Saus C, Sennino B, Peng S, et al. (2023) Neoantigen-targeted CD8 T cell responses with PD-1 blockade therapy. Nature
Foy SP, Jacoby K, Bota DA, et al. (2022) Non-viral precision T cell receptor replacement for personalized cell therapy. Nature
Cristea M, Chmielowski B, Funke R, et al. (2020) Abstract CT250: A Phase 1a/1b, open-label first-in-human study of the safety, tolerability, and feasibility of gene-edited autologous NeoTCR-T cells (NeoTCR-P1) administered to patients with locally advanced or metastatic solid tumors Cancer Research. 80
Sennino B, Conroy A, Purandare B, et al. (2020) Abstract 895: Coexpression of MHC class I-restricted neoTCRs and ectopic CD8 receptors in precision genome engineered CD4 T cells significantly potentiates antigen-specific effector functions Immunology. 80: 895-895
Dalmas O, Pan Z, Shieh C, et al. (2020) Abstract 3253: A high-throughput platform to produce neoE-HLA libraries for capturing neoE-specific T cells from the peripheral blood of patients with solid tumors Immunology
Jacoby K, Lu W, Nguyen D, et al. (2020) Abstract 2192: Non-viral genome engineering method allows highly efficient, single-step removal and precise insertion of multiple large genes Immunology. 80: 2192-2192
Peng S, Yuen B, Tan J, et al. (2019) Abstract 4042: Longitudinal monitoring of neoepitope-specific T cell repertoires in patient blood following cancer immunotherapy Cancer Research
Jacoby K, Moot R, Lu W, et al. (2019) Abstract 4783: Highly efficient, non-viral precision genome engineering for the generation of personalized neoepitope-specific adoptive T cell therapies Cancer Research. 79: 4783-4783
Peng S, Quach B, An D, et al. (2019) Abstract 1435: An ultra-sensitive and high-throughput technology (imPACT) for the identification and isolation of intrinsic and emergent neoepitope-specific T cells from the peripheral blood and TILs of cancer patients Cancer Research. 79: 1435-1435
Sennino B, Conroy A, Purandare B, et al. (2019) Abstract 1433: NeoTCR-P1, a novel neoepitope-specific adoptive cell therapy, consists of T cells with ‘younger’ phenotypes that rapidly proliferate and kill target cells upon recognition of cognate antigen Cancer Research. 79: 1433-1433
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