Rajnish A. Gupta, Ph.D.

Affiliations: 
2004 Vanderbilt University, Nashville, TN 
Area:
Oncology, Molecular Biology
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"Rajnish Gupta"

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Raymond N. DuBois grad student 2004 Vanderbilt
 (Peroxisome proliferator-activated receptor gamma (PPARgamma) is regulator of colorectal cancer cell growth and differentiation.)
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Publications

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Shah N, Jin K, Cruz LA, et al. (2013) HOXB13 mediates tamoxifen resistance and invasiveness in human breast cancer by suppressing ERα and inducing IL-6 expression. Cancer Research. 73: 5449-58
Gupta RA, Shah N, Wang KC, et al. (2010) Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis. Nature. 464: 1071-6
Gupta RA, Wang D, Katkuri S, et al. (2004) Activation of nuclear hormone receptor peroxisome proliferator-activated receptor-delta accelerates intestinal adenoma growth. Nature Medicine. 10: 245-7
Gupta RA, Tejada LV, Tong BJ, et al. (2003) Cyclooxygenase-1 is overexpressed and promotes angiogenic growth factor production in ovarian cancer. Cancer Research. 63: 906-11
Gupta RA, Sarraf P, Mueller E, et al. (2003) Peroxisome proliferator-activated receptor gamma-mediated differentiation: a mutation in colon cancer cells reveals divergent and cell type-specific mechanisms. The Journal of Biological Chemistry. 278: 22669-77
Daikoku T, Matsumoto H, Gupta RA, et al. (2003) Expression of hypoxia-inducible factors in the peri-implantation mouse uterus is regulated in a cell-specific and ovarian steroid hormone-dependent manner. Evidence for differential function of HIFs during early pregnancy. The Journal of Biological Chemistry. 278: 7683-91
Gupta RA, Sarraf P, Brockman JA, et al. (2003) Peroxisome proliferator-activated receptor gamma and transforming growth factor-beta pathways inhibit intestinal epithelial cell growth by regulating levels of TSC-22. The Journal of Biological Chemistry. 278: 7431-8
Gupta RA, DuBois RN, Wallace MC. (2002) New avenues for the prevention of colorectal cancer: targeting cyclo-oxygenase-2 activity. Best Practice & Research. Clinical Gastroenterology. 16: 945-56
Gupta RA, Dubois RN. (2002) Controversy: PPARgamma as a target for treatment of colorectal cancer. American Journal of Physiology. Gastrointestinal and Liver Physiology. 283: G266-9
Kozak KR, Gupta RA, Moody JS, et al. (2002) 15-Lipoxygenase metabolism of 2-arachidonylglycerol. Generation of a peroxisome proliferator-activated receptor alpha agonist. The Journal of Biological Chemistry. 277: 23278-86
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