Jeffrey Settleman
Affiliations: | Yale University, New Haven, CT |
Area:
Cell Biology, GeneticsGoogle:
"Jeffrey Settleman"Parents
Sign in to add mentorDaniel C. DiMaio | grad student | Yale (Chemistry Tree) | |
Robert A. Weinberg | post-doc | MIT |
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Publications
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Marcar L, Bardhan K, Gheorghiu L, et al. (2019) Acquired Resistance of EGFR-Mutated Lung Cancer to Tyrosine Kinase Inhibitor Treatment Promotes PARP Inhibitor Sensitivity. Cell Reports. 27: 3422-3432.e4 |
Wang VE, Doench J, Root D, et al. (2017) Abstract 3182: Cytoskeletal modulation results in increased tumor survival and drug resistance through attenuation of p53 dependent apoptosis Cancer Research. 77: 3182-3182 |
Wang VE, Settleman J, McCormic F. (2017) Abstract 1209: FGFR inhibition re-sensitizes BRAF/MEK dual resistant cells to the BRAF/MEK inhibitor combination Cancer Research. 77: 1209-1209 |
Pusapati R, Gao M, Daemen A, et al. (2016) Abstract B02: mTOR/S6K pathway-dependent metabolic reprogramming in cancer cells mediates resistance to glycolytic inhibitors Molecular Cancer Research. 14 |
Savage HM, O’Brien C, Moore H, et al. (2016) Abstract 372: Taselisib enhances the potency of ERBB inhibitors in biomarker-defined subsets of head and neck squamous carcinoma cell lines Cancer Research. 76: 372-372 |
Daemen A, Peterson D, Sahu N, et al. (2015) Metabolite profiling stratifies pancreatic ductal adenocarcinomas into subtypes with distinct sensitivities to metabolic inhibitors. Proceedings of the National Academy of Sciences of the United States of America. 112: E4410-7 |
Nair PM, Flores H, Gogineni A, et al. (2015) Enhancing the antitumor efficacy of a cell-surface death ligand by covalent membrane display. Proceedings of the National Academy of Sciences of the United States of America. 112: 5679-84 |
Kim Y, Apetri M, Luo B, et al. (2015) Differential Effects of Tyrosine Kinase Inhibitors on Normal and Oncogenic EGFR Signaling and Downstream Effectors. Molecular Cancer Research : McR. 13: 765-74 |
Klijn C, Durinck S, Stawiski EW, et al. (2015) A comprehensive transcriptional portrait of human cancer cell lines. Nature Biotechnology. 33: 306-12 |
Dompe NA, Lin E, Peng J, et al. (2015) Abstract B22: Potential combinatorial strategies to overcome drug resistance in BRAF-mutant melanoma Clinical Cancer Research. 21 |