Long-Sheng Chang

Affiliations: 
Ohio State University, Columbus, Columbus, OH 
Area:
Molecular Biology
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"Long-Sheng Chang"
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Chang LS, Oblinger JL, Smith AE, et al. (2021) Brigatinib causes tumor shrinkage in both NF2-deficient meningioma and schwannoma through inhibition of multiple tyrosine kinases but not ALK. Plos One. 16: e0252048
Chang LS, Oblinger JL, Burns SS, et al. (2019) Targeting protein translation by rocaglamide and didesmethylrocaglamide to treat MPNST and other sarcomas. Molecular Cancer Therapeutics
Allaway R, Angus SP, et al. (2018) Traditional and systems biology based drug discovery for the rare tumor syndrome neurofibromatosis type 2. Plos One. 13: e0197350
Beauchamp R, Erdin S, Angus S, et al. (2018) CSIG-42. HIGH THROUGHPUT KINOME AND TRANSCRIPTOME ANALYSES REVEAL NOVEL THERAPEUTIC TARGETS IN NF2-DEFICIENT MENINGIOMA Neuro-Oncology. 20: vi52-vi52
Fuse MA, Klingeman Plati S, Burns SS, et al. (2017) Combination Therapy With c-Met and Src Inhibitors Induces Caspase-Dependent Apoptosis of Merlin-Deficient Schwann Cells and Suppresses Growth of Schwannoma Cells. Molecular Cancer Therapeutics
Oblinger JL, Burns SS, Huang J, et al. (2017) Overexpression of eIF4F components in meningiomas and suppression of meningioma cell growth by inhibiting translation initiation. Experimental Neurology
Petrilli AM, Garcia J, Bott M, et al. (2017) Ponatinib promotes a G1 cell-cycle arrest of merlin/NF2-deficient human schwann cells. Oncotarget
Burns SS, Chang LS. (2016) Generation of Noninvasive, Quantifiable, Orthotopic Animal Models for NF2-Associated Schwannoma and Meningioma. Methods in Molecular Biology (Clifton, N.J.). 1427: 59-72
Oblinger JL, Burns SS, Akhmametyeva EM, et al. (2016) Components of the eIF4F complex are potential therapeutic targets for malignant peripheral nerve sheath tumors and vestibular schwannomas. Neuro-Oncology
Chow HY, Dong B, Duron SG, et al. (2015) Group I Paks as therapeutic targets in NF2-deficient meningioma. Oncotarget. 6: 1981-94
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