Careen K. Tang

Affiliations: 
Tumor Biology Georgetown University, Washington, DC 
Area:
Cell Biology, Molecular Biology, Oncology
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"Careen Tang"
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Publications

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Chang KY, Tsai SY, Chen SH, et al. (2013) Dissecting the EGFR-PI3K-AKT pathway in oral cancer highlights the role of the EGFR variant III and its clinical relevance. Journal of Biomedical Science. 20: 43
Chang K, Tsai S, Chen S, et al. (2013) Abstract 2390: EGFR variant III act as the major determinant factors in the EGFR/PI3K/AKT pathway for the survival outcome of oral cancer patients. Cancer Research. 73: 2390-2390
Feng H, Hu B, Jarzynka MJ, et al. (2012) Phosphorylation of dedicator of cytokinesis 1 (Dock180) at tyrosine residue Y722 by Src family kinases mediates EGFRvIII-driven glioblastoma tumorigenesis. Proceedings of the National Academy of Sciences of the United States of America. 109: 3018-23
Su H, Sobrino Najul EJ, Toth TA, et al. (2011) Chemokine receptor CXCR4-mediated transformation of mammary epithelial cells by enhancing multiple RTKs expression and deregulation of the p53/MDM2 axis. Cancer Letters. 307: 132-40
Rahimi M, Toth TA, Tang CK. (2011) CXCR4 suppression attenuates EGFRvIII-mediated invasion and induces p38 MAPK-dependent protein trafficking and degradation of EGFRvIII in breast cancer cells. Cancer Letters. 306: 43-51
Rahimi M, Huang KL, Tang CK. (2010) 3,3'-Diindolylmethane (DIM) inhibits the growth and invasion of drug-resistant human cancer cells expressing EGFR mutants. Cancer Letters. 295: 59-68
Rahimi M, George J, Tang C. (2010) EGFR variant-mediated invasion by enhanced CXCR4 expression through transcriptional and post-translational mechanisms. International Journal of Cancer. 126: 1850-60
Zhang Y, Su H, Rahimi M, et al. (2009) EGFRvIII-induced estrogen-independence, tamoxifen-resistance phenotype correlates with PgR expression and modulation of apoptotic molecules in breast cancer. International Journal of Cancer. 125: 2021-8
O'Malley S, Su H, Zhang T, et al. (2009) TOB suppresses breast cancer tumorigenesis. International Journal of Cancer. 125: 1805-13
Yu H, Gong X, Luo X, et al. (2008) Co-expression of EGFRvIII with ErbB-2 enhances tumorigenesis: EGFRvIII mediated constitutively activated and sustained signaling pathways, whereas EGF-induced a transient effect on EGFR-mediated signaling pathways. Cancer Biology & Therapy. 7: 1818-28
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