Samuel A. Black, Ph.D.

Affiliations: 
2007 Boston University, Boston, MA, United States 
Area:
Dentistry, Molecular Biology, Cell Biology
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"Samuel Black"

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Philip Trackman grad student 2007 Boston University
 (Signal transduction pathways mediating the expression of connective tissue growth factor by TGF[beta]1 in human gingival fibroblasts: Regulation by prostaglandin-E2.)
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Bahammam M, Black SA, Sume SS, et al. (2013) Requirement for active glycogen synthase kinase-3β in TGF-β1 upregulation of connective tissue growth factor (CCN2/CTGF) levels in human gingival fibroblasts. American Journal of Physiology. Cell Physiology. 305: C581-90
Black SA, Trackman PC. (2008) Transforming growth factor-beta1 (TGFbeta1) stimulates connective tissue growth factor (CCN2/CTGF) expression in human gingival fibroblasts through a RhoA-independent, Rac1/Cdc42-dependent mechanism: statins with forskolin block TGFbeta1-induced CCN2/CTGF expression. The Journal of Biological Chemistry. 283: 10835-47
Black SA, Palamakumbura AH, Stan M, et al. (2007) Tissue-specific mechanisms for CCN2/CTGF persistence in fibrotic gingiva: interactions between cAMP and MAPK signaling pathways, and prostaglandin E2-EP3 receptor mediated activation of the c-JUN N-terminal kinase. The Journal of Biological Chemistry. 282: 15416-29
Kantarci A, Black SA, Xydas CE, et al. (2006) Epithelial and connective tissue cell CTGF/CCN2 expression in gingival fibrosis. The Journal of Pathology. 210: 59-66
Heng EC, Huang Y, Black SA, et al. (2006) CCN2, connective tissue growth factor, stimulates collagen deposition by gingival fibroblasts via module 3 and alpha6- and beta1 integrins. Journal of Cellular Biochemistry. 98: 409-20
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