Mario A. Shields, Ph.D.

Affiliations: 
2012 Integrated Graduate Program in the Life Sciences Northwestern University, Evanston, IL 
Area:
General Biology, Cell Biology, Molecular Biology, Oncology
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"Mario Shields"

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Hidayatullah G. Munshi grad student 2012 Northwestern
 (The Interplay between Fibrosis and Snail Family of Transcription Factors in Pancreatic Cancer.)
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Publications

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Shields MA, Metropulos AE, Spaulding C, et al. (2023) BET inhibition rescues ciliogenesis and ameliorates pancreatitis-driven phenotypic changes in mice with Par3 loss. Biorxiv : the Preprint Server For Biology
Pham TN, Spaulding C, Shields MA, et al. (2022) Inhibition of MNKs promotes macrophage immunosuppressive phenotype to limit CD8+ T cell antitumor immunity. Jci Insight. 7
Shields MA, Spaulding C, Metropulos AE, et al. (2022) Gα13 loss in Kras/Tp53 mouse model of pancreatic tumorigenesis promotes tumors susceptible to rapamycin. Cell Reports. 38: 110441
Pham TND, Shields MA, Spaulding C, et al. (2021) Preclinical Models of Pancreatic Ductal Adenocarcinoma and Their Utility in Immunotherapy Studies. Cancers. 13
Barth ND, Subiros-Funosas R, Mendive-Tapia L, et al. (2020) A fluorogenic cyclic peptide for imaging and quantification of drug-induced apoptosis. Nature Communications. 11: 4027
Pham TND, Stempel S, Shields MA, et al. (2019) Quercetin Enhances the Anti-Tumor Effects of BET Inhibitors by Suppressing hnRNPA1. International Journal of Molecular Sciences. 20
Pham T, Stempel S, Shields M, et al. (2019) Abstract 2086: Targeting the MNK effector hnRNPA1 enhances the efficacy of BET inhibitors in cancer cells Cancer Research
Albrengues J, Shields MA, Ng D, et al. (2018) Neutrophil extracellular traps produced during inflammation awaken dormant cancer cells in mice. Science (New York, N.Y.). 361
Ebine K, Kumar K, Pham TN, et al. (2018) Interplay between interferon regulatory factor 1 and BRD4 in the regulation of PD-L1 in pancreatic stellate cells. Scientific Reports. 8: 13225
Shields M, Maguin P, Giuliano C, et al. (2018) Abstract B44: Lysyl oxidases suppress pancreatic cancer progression and inhibit FAK and ERK signaling Cancer Research. 78
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