David J. DeGraff, Ph.D.

Affiliations: 
2008 Department of Biological Sciences University of Delaware, Newark, DE, United States 
Area:
Physiology Biology, Cell Biology, Molecular Biology
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"David DeGraff"

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Robert A. Sikes grad student 2008 University of Delaware
 (Implications for the androgenic regulation of IGFBP-2 in the development of metastatic and androgen independent prostate cancer.)
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Publications

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Shuman L, Pham J, Wildermuth T, et al. (2023) Urothelium-specific expression of mutationally activated Pik3ca initiates early lesions of non-invasive bladder cancer. The American Journal of Pathology
Warrick JI, Hu W, Yamashita H, et al. (2022) FOXA1 repression drives lineage plasticity and immune heterogeneity in bladder cancers with squamous differentiation. Nature Communications. 13: 6575
Walter V, DeGraff DJ, Yamashita H. (2022) Characterization of laminin-332 gene expression in molecular subtypes of human bladder cancer. American Journal of Clinical and Experimental Urology. 10: 311-319
Torab P, Yan Y, Ahmed M, et al. (2021) Intratumoral Heterogeneity Promotes Collective Cancer Invasion through NOTCH1 Variation. Cells. 10
Iyyanki T, Zhang B, Wang Q, et al. (2021) Subtype-associated epigenomic landscape and 3D genome structure in bladder cancer. Genome Biology. 22: 105
Connelly ZM, Jin R, Zhang J, et al. (2020) FOXA2 promotes prostate cancer growth in the bone. American Journal of Translational Research. 12: 5619-5629
Torab P, Yan Y, Yamashita H, et al. (2020) Three-Dimensional Microtumors for Probing Heterogeneity of Invasive Bladder Cancer. Analytical Chemistry
Meeks JJ, Al-Ahmadie H, Faltas BM, et al. (2020) Genomic heterogeneity in bladder cancer: challenges and possible solutions to improve outcomes. Nature Reviews. Urology
Russo M, Newell JM, Budurlean L, et al. (2020) Mutational profile of endometrial hyperplasia and risk of progression to endometrioid adenocarcinoma. Cancer
Li H, Zhang Q, Shuman L, et al. (2020) Evaluation of PD-L1 and other immune markers in bladder urothelial carcinoma stratified by histologic variants and molecular subtypes. Scientific Reports. 10: 1439
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