Annie Bourdeau, Ph.D.

Affiliations: 
2000 University of Toronto, Toronto, ON, Canada 
Area:
Immunology
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"Annie Bourdeau"

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Michelle Letarte grad student 2000 University of Toronto
 (Understanding the function of endoglin through the generation and characterization of endoglin deficient mice and the study of patients with hereditary hemorrhagic telangiectasia.)
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Publications

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Bourdeau A, Van Slyke P, Kim H, et al. (2016) Vasculotide, an Angiopoietin-1 mimetic, ameliorates several features of experimental atopic dermatitis-like disease. Bmc Research Notes. 9: 289
Bourdeau A, Trop S, Doody KM, et al. (2013) Inhibition of T cell protein tyrosine phosphatase enhances interleukin-18-dependent hematopoietic stem cell expansion. Stem Cells (Dayton, Ohio). 31: 293-304
Heinonen KM, Bourdeau A, Doody KM, et al. (2009) Protein tyrosine phosphatases PTP-1B and TC-PTP play nonredundant roles in macrophage development and IFN-gamma signaling. Proceedings of the National Academy of Sciences of the United States of America. 106: 9368-72
Doody KM, Bourdeau A, Tremblay ML. (2009) T-cell protein tyrosine phosphatase is a key regulator in immune cell signaling: lessons from the knockout mouse model and implications in human disease. Immunological Reviews. 228: 325-41
Trop S, Tremblay ML, Bourdeau A. (2008) Modulation of bone marrow-derived endothelial progenitor cell activity by protein tyrosine phosphatases. Trends in Cardiovascular Medicine. 18: 180-6
Sirois J, Côté JF, Charest A, et al. (2006) Essential function of PTP-PEST during mouse embryonic vascularization, mesenchyme formation, neurogenesis and early liver development. Mechanisms of Development. 123: 869-80
Simoncic PD, Bourdeau A, Lee-Loy A, et al. (2006) T-cell protein tyrosine phosphatase (Tcptp) is a negative regulator of colony-stimulating factor 1 signaling and macrophage differentiation. Molecular and Cellular Biology. 26: 4149-60
Heinonen KM, Dubé N, Bourdeau A, et al. (2006) Protein tyrosine phosphatase 1B negatively regulates macrophage development through CSF-1 signaling. Proceedings of the National Academy of Sciences of the United States of America. 103: 2776-81
Dubé N, Bourdeau A, Heinonen KM, et al. (2005) Genetic ablation of protein tyrosine phosphatase 1B accelerates lymphomagenesis of p53-null mice through the regulation of B-cell development. Cancer Research. 65: 10088-95
Bourdeau A, Dubé N, Tremblay ML. (2005) Cytoplasmic protein tyrosine phosphatases, regulation and function: the roles of PTP1B and TC-PTP. Current Opinion in Cell Biology. 17: 203-9
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