Lawrence B. Gardner
Affiliations: | Basic Medical Science | New York University, New York, NY, United States |
Area:
Cell BiologyGoogle:
"Lawrence Gardner"
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Publications
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| Daley D, Mani VR, Mohan N, et al. (2017) Dectin 1 activation on macrophages by galectin 9 promotes pancreatic carcinoma and peritumoral immune tolerance. Nature Medicine |
| Wengrod JC, Gardner LB. (2015) Cellular adaptation to nutrient deprivation: crosstalk between the mTORC1 and eIF2α signaling pathways and implications for autophagy. Cell Cycle (Georgetown, Tex.). 14: 2571-7 |
| Wengrod J, Wang D, Weiss S, et al. (2015) Phosphorylation of eIF2α triggered by mTORC1 inhibition and PP6C activation is required for autophagy and is aberrant in PP6C-mutated melanoma. Science Signaling. 8: ra27 |
| Martin L, Gardner LB. (2014) Stress-induced inhibition of nonsense-mediated RNA decay regulates intracellular cystine transport and intracellular glutathione through regulation of the cystine/glutamate exchanger SLC7A11. Oncogene |
| Martin L, Grigoryan A, Wang D, et al. (2014) Identification and characterization of small molecules that inhibit nonsense-mediated RNA decay and suppress nonsense p53 mutations. Cancer Research. 74: 3104-13 |
| Gold HL, Wengrod J, de Miera EV, et al. (2014) PP6C hotspot mutations in melanoma display sensitivity to Aurora kinase inhibition. Molecular Cancer Research : McR. 12: 433-9 |
| Wengrod J, Martin L, Wang D, et al. (2013) Inhibition of nonsense-mediated RNA decay activates autophagy. Molecular and Cellular Biology. 33: 2128-35 |
| Karam R, Wengrod J, Gardner LB, et al. (2013) Regulation of nonsense-mediated mRNA decay: implications for physiology and disease. Biochimica Et Biophysica Acta. 1829: 624-33 |
| Gold HL, Wengrod J, Tian J, et al. (2013) The clinical and biologic impact of PPP6C mutations in melanoma. Journal of Clinical Oncology. 31: 9067-9067 |
| Martin L, Rainey M, Santocanale C, et al. (2012) Hypoxic activation of ATR and the suppression of the initiation of DNA replication through cdc6 degradation. Oncogene. 31: 4076-84 |