Phillip M. Shelton, Ph.D.

Affiliations: 
2013 Toxicology University of Maryland School of Medicine, Baltimore, MD, United States 
Area:
Toxicology, Pharmacology, Oncology
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"Phillip Shelton"

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Anil K. Jaiswal grad student 2013 University of Maryland Medical School
 (Glycogen synthase kinase 3-beta (GSK3beta) is a central regulator in the non-canonical NF-E2 related factor (Nrf2) antioxidant response.)
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Publications

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Nakanishi Y, Duran A, L'Hermitte A, et al. (2018) Simultaneous Loss of Both Atypical Protein Kinase C Genes in the Intestinal Epithelium Drives Serrated Intestinal Cancer by Impairing Immunosurveillance. Immunity
Reina-Campos M, Shelton PM, Diaz-Meco MT, et al. (2018) Metabolic reprogramming of the tumor microenvironment by p62 and its partners. Biochimica Et Biophysica Acta
Niture SK, Jain AK, Shelton PM, et al. (2017) Src subfamily kinases regulate nuclear export and degradation of transcription factor Nrf2 to switch off Nrf2-mediated antioxidant activation of cytoprotective gene expression. The Journal of Biological Chemistry. 292: 2048
Niture SK, Jain AK, Shelton PM, et al. (2016) Src subfamily kinases regulate nuclear export and degradation of transcription factor Nrf2 to swtich off Nrf2-mediated antioxidant activation of cytoprotective gene expression. The Journal of Biological Chemistry. 291: 1199
Llado V, Nakanishi Y, Duran A, et al. (2015) Repression of Intestinal Stem Cell Function and Tumorigenesis through Direct Phosphorylation of β-Catenin and Yap by PKCζ Cell Reports
Stark K, Burger A, Wu J, et al. (2013) Reactivation of estrogen receptor α by vorinostat sensitizes mesenchymal-like triple-negative breast cancer to aminoflavone, a ligand of the aryl hydrocarbon receptor. Plos One. 8: e74525
Shelton P, Jaiswal AK. (2013) The transcription factor NF-E2-related factor 2 (Nrf2): a protooncogene? Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 27: 414-23
Niture SK, Jain AK, Shelton PM, et al. (2011) Src subfamily kinases regulate nuclear export and degradation of transcription factor Nrf2 to switch off Nrf2-mediated antioxidant activation of cytoprotective gene expression Journal of Biological Chemistry. 286: 28821-28832
Stark K, Nguyen B, Shelton P, et al. (2010) Abstract 2765: Cytoplasmic expression of the aryl hydrocarbon receptor elicits sensitivity and nuclear expression resistance to aminoflavone prodrug Cancer Research. 70: 2765-2765
Shelton P, Nguyen B, Chen A, et al. (2009) Transcriptional gene expression profiles indicate response of breast cancer cell lines to aminoflavone prodrug. Cancer Research. 69: 2153
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