Patrick R. Hagner, Ph.D.

Affiliations: 
2010 Molecular Medicine University of Maryland School of Medicine, Baltimore, MD, United States 
Area:
Molecular Biology
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"Patrick Hagner"

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Tony Passaniti grad student 2010 University of Maryland Medical School
 (Targeting the translational machinery as a novel treatment strategy for non -Hodgkin lymphoma.)
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Publications

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Apollonio B, Spada F, Petrov N, et al. (2023) Tumor-activated lymph node fibroblasts suppress T cell function in diffuse large B cell lymphoma. The Journal of Clinical Investigation
Ribrag V, Chavez JC, Boccomini C, et al. (2022) Phase Ib study of combinations of avadomide (CC-122), CC-223, CC-292, and rituximab in patients with relapsed/refractory diffuse large B-cell lymphoma. Ejhaem. 3: 139-153
Wu W, Nelson G, Koch R, et al. (2021) Overcoming IMiD Resistance in T-cell Lymphomas Through Potent Degradation of ZFP91 and IKZF1. Blood
Michot JM, Bouabdallah R, Vitolo U, et al. (2020) Avadomide plus obinutuzumab in patients with relapsed or refractory B-cell non-Hodgkin lymphoma (CC-122-NHL-001): a multicentre, dose escalation and expansion phase 1 study. The Lancet. Haematology
Risueno A, Hagner PR, Towfic F, et al. (2020) Leveraging Gene Expression Subgroups to Classify DLBCL Patients and Enrich for Clinical Benefit to a Novel Agent. Blood
Carpio C, Bouabdallah R, Ysebaert L, et al. (2020) Avadomide monotherapy in relapsed/refractory DLBCL: Safety, efficacy, and a predictive gene classifier. Blood
Mehta-Shah N, Chavez JC, Abrisqueta P, et al. (2020) Phase I/II study of avadomide (CC-122) in combination with R-CHOP for newly diagnosed DLBCL. Journal of Clinical Oncology. 38: 3501-3501
Chiu H, Trisal P, Bjorklund C, et al. (2019) Combination lenalidomide-rituximab immunotherapy activates anti-tumour immunity and induces tumour cell death by complementary mechanisms of action in follicular lymphoma. British Journal of Haematology
Hagner PR, Chiu H, Chopra VS, et al. (2019) Interactome of Aiolos/Ikaros in Diffuse Large B-Cell Lymphoma (DLBCL) Reveals Novel Combination of Cereblon Modulators (CELMoD) and Histone Deacetylase (HDAC) Inhibitors Blood. 134: 306-306
Hagner PR, Waldman M, Gray FD, et al. (2019) Targeting B-Cell Maturation Antigen (BCMA) with CC-93269, a 2+1 T Cell Engager, Elicits Significant Apoptosis in Diffuse Large B-Cell Lymphoma Preclinical Models Blood. 134: 1580-1580
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