Zhixiang He
Affiliations: | 2013-2016 | School of Life Sciences, Xiamen University |
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Sign in to add mentor| Xianming DENG | grad student | 2013-2016 | School of Life Sciences, Xiamen University |
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| Arwood ML, Liu Y, Harkins SK, et al. (2023) New scaffolds for type II JAK2 inhibitors overcome the acquired G993A resistance mutation. Cell Chemical Biology |
| Lu W, Liu Y, Gao Y, et al. (2023) Development of a Covalent Inhibitor of c-Jun N-Terminal Protein Kinase (JNK) 2/3 with Selectivity over JNK1. Journal of Medicinal Chemistry. 66: 3356-3371 |
| Fan M, Lu W, Che J, et al. (2022) Covalent disruptor of YAP-TEAD association suppresses defective hippo signaling. Elife. 11 |
| Du G, Jiang J, Henning NJ, et al. (2022) Exploring the target scope of KEAP1 E3 ligase-based PROTACs. Cell Chemical Biology |
| Powell CE, Du G, Bushman JW, et al. (2021) Selective degradation-inducing probes for studying cereblon (CRBN) biology. Rsc Medicinal Chemistry. 12: 1381-1390 |
| Jiang J, Jiang B, He Z, et al. (2020) Discovery of Covalent MKK4/7 Dual Inhibitor. Cell Chemical Biology |
| Powell CE, Du G, Che J, et al. (2020) Selective Degradation of GSPT1 by Cereblon Modulators Identified via a Focused Combinatorial Library. Acs Chemical Biology |
| Liu Y, Hao M, Leggett A, et al. (2020) Discovery of MFH290: A Potent and Highly Selective Covalent Inhibitor for Cyclin-Dependent Kinase 12/13. Journal of Medicinal Chemistry |
| Gray NS, Teng M, Jiang J, et al. (2020) Development of CDK2 and CDK5 Dual Degrader TMX-2172. Angewandte Chemie (International Ed. in English) |
| Liu J, Chen H, Ma L, et al. (2020) Light-induced control of protein destruction by opto-PROTAC. Science Advances. 6: eaay5154 |