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Xu Wu

Affiliations: 
2005-2011 Genomics Institute of the Novartis Research Foundation 
 2011- MGH/Harvard, Boston, MA, United States 
Area:
lipid biochemistry, chemical biology, developmental biology and cancer
Website:
www.xwulab.org
Google:
"Xu Wu"
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Parents

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Peter G. Schultz grad student 2001-2004 Scripps Research Institute

Children

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Yang S. Brooks post-doc MGH/Harvard
Elaina PuiYee Chan post-doc MGH/Harvard
Baoen Chen post-doc MGH/Harvard
Michael DeRan post-doc MGH/Harvard
Jianjun Fu post-doc MGH/Harvard
Gopala K. Jarugumilli post-doc MGH/Harvard
Jixiao Niu post-doc MGH/Harvard
Yang Sunny Sun post-doc MGH/Harvard
Baohui Zheng post-doc MGH/Harvard
Haiyan Tao post-doc 2006-2009 GNF Novartis
Jiayi Yang post-doc 2009-2011 GNF Novartis (Cell Biology Tree)

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Publications

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Azzi A, Tao Z, Sun Y, et al. (2023) The circadian clock protein Cryptochrome 1 is a direct target and feedback regulator of the Hippo pathway. Iscience. 26: 107449
Hu L, Sun Y, Liu S, et al. (2022) Discovery of a new class of reversible TEA-domain transcription factor inhibitors with a novel binding mode. Elife. 11
Sun Y, Hu L, Tao Z, et al. (2022) Pharmacological blockade of TEAD-YAP reveals its therapeutic limitation in cancer cells. Nature Communications. 13: 6744
Cotton JL, Dang K, Hu L, et al. (2022) PTEN and LKB1 are differentially required in Gli1-expressing mesenchymal cells to suppress gastrointestinal polyposis. Cell Reports. 40: 111125
Chen B, Guarino C, Azzi A, et al. (2022) Regulation of Cell Polarity by Posttranslational Protein Palmitoylation. Methods in Molecular Biology (Clifton, N.J.). 2438: 107-121
He L, Jhong JH, Chen Q, et al. (2021) Global characterization of macrophage polarization mechanisms and identification of M2-type polarization inhibitors. Cell Reports. 37: 109955
Shalhout SZ, Yang PY, Grzelak EM, et al. (2021) YAP-dependent proliferation by a small molecule targeting annexin A2. Nature Chemical Biology
Niu J, Sun Y, Chen B, et al. (2020) Retraction Note: Fatty acids and cancer-amplified ZDHHC19 promote STAT3 activation through S-palmitoylation. Nature
Li Q, Sun Y, Jarugumilli GK, et al. (2020) Lats1/2 Sustain Intestinal Stem Cells and Wnt Activation through TEAD-Dependent and Independent Transcription. Cell Stem Cell
Wu X. (2020) Abstract IA12: Targeting autopalmitoylation of TEAD transcription factors Molecular Cancer Research. 18
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