Tingjian Chen
Affiliations: | 2011- | Scripps Research Institute, La Jolla, La Jolla, CA, United States |
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| Cao Y, Bai J, Zou J, et al. (2023) One-Pot Enzymatic Preparation of Oligonucleotides with an Expanded Genetic Alphabet via Controlled Pause and Restart of Primer Extension: Making Unnatural Out of Natural. Acs Synthetic Biology. 12: 2691-2706 |
| Qin Y, Ma X, Tao R, et al. (2023) Synthesis, Reverse Transcription, Replication, and Inter-Transcription of 2'-Modified Nucleic Acids with Evolved Thermophilic Polymerases: Efforts toward Multidimensional Expansion of the Central Dogma. Acs Synthetic Biology. 12: 2616-2631 |
| Bai J, Zou J, Cao Y, et al. (2023) Recognition of an Unnatural Base Pair by Tool Enzymes from Bacteriophages and Its Application in the Enzymatic Preparation of DNA with an Expanded Genetic Alphabet. Acs Synthetic Biology. 12: 2676-2690 |
| Wang G, Du Y, Ma X, et al. (2022) Thermophilic Nucleic Acid Polymerases and Their Application in Xenobiology. International Journal of Molecular Sciences. 23 |
| Wang G, He C, Zou J, et al. (2022) Enzymatic Synthesis of DNA with an Expanded Genetic Alphabet Using Terminal Deoxynucleotidyl Transferase. Acs Synthetic Biology. 11: 4142-4155 |
| Sun L, Ma X, Zhang B, et al. (2022) From polymerase engineering to semi-synthetic life: artificial expansion of the central dogma. Rsc Chemical Biology. 3: 1173-1197 |
| Guo YY, Zhang R, Huo B, et al. (2022) Site-specific unnatural base excision visible light. Chemical Communications (Cambridge, England) |
| Song P, Zhang R, He C, et al. (2021) Transcription, Reverse Transcription, and Amplification of Backbone-Modified Nucleic Acids with Laboratory-Evolved Thermophilic DNA Polymerases. Current Protocols. 1: e188 |
| Shao Q, Chen T, Sheng K, et al. (2020) Selection of Aptamers with Large Hydrophobic 2'-Substituents. Journal of the American Chemical Society |
| Liu Z, Chen T, Romesberg FE. (2017) Evolved polymerases facilitate selection of fully 2'-OMe-modified aptamers. Chemical Science. 8: 8179-8182 |