Christopher Halbrook
Affiliations: | 2016- | Molecular and Integrative Physiology | University of Michigan, Ann Arbor, Ann Arbor, MI |
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| Radyk MD, Nelson BS, Halbrook CJ, et al. (2023) Glucose-6-phosphate dehydrogenase deficiency accelerates pancreatic acinar-to-ductal metaplasia. Biorxiv : the Preprint Server For Biology |
| Nwosu ZC, Ward MH, Sajjakulnukit P, et al. (2023) Uridine-derived ribose fuels glucose-restricted pancreatic cancer. Nature |
| Halbrook CJ, Lyssiotis CA, Pasca di Magliano M, et al. (2023) Pancreatic cancer: Advances and challenges. Cell. 186: 1729-1754 |
| Menjivar RE, Nwosu ZC, Du W, et al. (2023) Arginase 1 is a key driver of immune suppression in pancreatic cancer. Elife. 12 |
| Halbrook CJ, Thurston G, Boyer S, et al. (2022) Differential integrated stress response and asparagine production drive symbiosis and therapy resistance of pancreatic adenocarcinoma cells. Nature Cancer. 3: 1386-1403 |
| Kerk S, Lin L, Myers AL, et al. (2022) Metabolic requirement for GOT2 in pancreatic cancer depends on environmental context. Elife. 11 |
| Boyer S, Lee HJ, Steele N, et al. (2022) Multiomic characterization of pancreatic cancer-associated macrophage polarization reveals deregulated metabolic programs driven by the GM-CSF-PI3K pathway. Elife. 11 |
| Kim PK, Halbrook CJ, Kerk SA, et al. (2021) Hyaluronic acid fuels pancreatic cancer cell growth. Elife. 10 |
| Kremer DM, Nelson BS, Lin L, et al. (2021) GOT1 inhibition promotes pancreatic cancer cell death by ferroptosis. Nature Communications. 12: 4860 |
| Krall AS, Mullen PJ, Surjono F, et al. (2021) Asparagine couples mitochondrial respiration to ATF4 activity and tumor growth. Cell Metabolism |