Alejandro J. Vila

Affiliations: 
Organic Chemistry Universidad Nacional de Rosario 
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"Alejandro Vila"
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Zhao Z, Shen X, Chen S, et al. (2023) Gating interactions steer loop conformational changes in the active site of the L1 metallo-β-lactamase. Elife. 12
McCann C, Quinteros M, Adelugba I, et al. (2022) The mitochondrial Cu transporter PiC2 (SLC25A3) is a target of MTF1 and contributes to the development of skeletal muscle . Frontiers in Molecular Biosciences. 9: 1037941
Rossi MA, Palzkill T, Almeida FCL, et al. (2022) Slow protein dynamics elicits new enzymatic functions by means of epistatic interactions. Molecular Biology and Evolution
Colque CA, Albarracín Orio AG, Tomatis PE, et al. (2022) Longitudinal Evolution of the Pseudomonas-Derived Cephalosporinase (PDC) Structure and Activity in a Cystic Fibrosis Patient Treated with β-Lactams. Mbio. e0166322
Szuster J, Leguto AJ, Zitare UA, et al. (2022) Electrochemical characterization of an engineered red copper protein featuring an unprecedented entropic control of the reduction potential. Bioelectrochemistry (Amsterdam, Netherlands). 146: 108095
Bahr G, González LJ, Vila AJ. (2021) Metallo-β-lactamases and a tug-of-war for the available zinc at the host-pathogen interface. Current Opinion in Chemical Biology. 66: 102103
Martínez MMB, Bonomo RA, Vila AJ, et al. (2021) On the Offensive: the Role of Outer Membrane Vesicles in the Successful Dissemination of New Delhi Metallo-β-lactamase (NDM-1). Mbio. e0183621
Hinchliffe P, Moreno DM, Rossi MA, et al. (2021) 2-Mercaptomethyl Thiazolidines (MMTZs) Inhibit All Metallo-β-Lactamase Classes by Maintaining a Conserved Binding Mode. Acs Infectious Diseases
López C, Prunotto A, Bahr G, et al. (2021) Specific protein-membrane interactions promote packaging of metallo-β-lactamases into outer membrane vesicles. Antimicrobial Agents and Chemotherapy. AAC0050721
Mojica MF, Rossi MA, Vila AJ, et al. (2021) The urgent need for metallo-β-lactamase inhibitors: an unattended global threat. The Lancet. Infectious Diseases
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