Shom Goel, M.D., Ph.D.

Affiliations: 
Cancer Biology Dana-Farber Cancer Institute, Boston, MA, United States 
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"Shom Goel"
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Dietrich C, Trub A, Ahn A, et al. (2023) INX-315, a selective CDK2 inhibitor, induces cell cycle arrest and senescence in solid tumors. Cancer Discovery
Tolaney SM, Goel S, Nadal J, et al. (2023) Overall survival and exploratory biomarker analyses of abemaciclib plus trastuzumab with or without fulvestrant vs trastuzumab plus chemotherapy in HR+, HER2+ metastatic breast cancer patients. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research
Tolaney SM, Goel S, Appiah AK, et al. (2023) Abemaciclib plus trastuzumab with or without fulvestrant versus trastuzumab plus standard-of-care chemotherapy in women with HR+, HER2+ advanced breast cancer: plain language summary of the monarcHER study. Future Oncology (London, England)
Ali LR, Garrido-Castro AC, Lenehan PJ, et al. (2023) PD-1 blockade and CDK4/6 inhibition augment nonoverlapping features of T cell activation in cancer. The Journal of Experimental Medicine. 220
Goel S, Chandarlapaty S. (2022) Emerging Therapies for Breast Cancer. Cold Spring Harbor Perspectives in Medicine
Goel S, Tan AR, Rugo HS, et al. (2022) Trilaciclib prior to gemcitabine plus carboplatin for metastatic triple-negative breast cancer: phase III PRESERVE 2. Future Oncology (London, England)
Pernas S, Guerriero JL, Naumenko S, et al. (2022) Early on-treatment transcriptional profiling as a tool for improving pathological response prediction in HER2-positive inflammatory breast cancer. Therapeutic Advances in Medical Oncology. 14: 17588359221113269
Wander SA, O'Brien N, Litchfield LM, et al. (2022) Targeting CDK4 and 6 in Cancer Therapy: Emerging Preclinical Insights Related to Abemaciclib. The Oncologist
Goel S, Bergholz JS, Zhao JJ. (2022) Targeting CDK4 and CDK6 in cancer. Nature Reviews. Cancer
Watt AC, Goel S. (2022) Cellular mechanisms underlying response and resistance to CDK4/6 inhibitors in the treatment of hormone receptor-positive breast cancer. Breast Cancer Research : Bcr. 24: 17
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