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Robert Tokhunts, PhD, MD.

Affiliations: 
1999-2004 Forensic Science John Jay College of Criminal Justice, CUNY, New York, NY, United States 
 2006-2012 Pharmacology and Toxicology Geisel School of Medicine at Dartmouth, Hanover, NH, United States 
 2010-2012 Surgical Oncology University of Miami Miller School of Medicine, Miami, FL, United States 
 2012-2014 Neuroscience Johns Hopkins Neuroscience 
 2014-2018 Medicine Geisel School of Medicine at Dartmouth, Hanover, NH, United States 
Area:
NMDA excitotoxicity, Heme degradation, Hedgehog Signaling
Website:
http://neuroscience.jhu.edu/research/faculty/83
Google:
"Robert Tokhunts"
Bio:

Geisel School of Medicine at Dartmouth: MD
Johns Hopkins Medicine: Solomon Snyder Department of Neuroscience: Neuroscientist
University of Miami Miller School of Medicine: Visiting Scholar
Geisel School of Medicine at Dartmouth: PhD
NYC Office of Chief Medical Examiner: Forensic Toxicologist
John Jay College of Criminal Justice: Forensic Science, BS: Summa Cum Laude

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Parents

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Ethan Dmitrovsky grad student 2006-2012 Dartmouth Medical School
David J Robbins grad student 2006-2012 Dartmouth Medical School
 (Mentor)
Solomon H. Snyder post-doc 2012-2014 Johns Hopkins Medical School/HHMI (Neurotree)
 (Mentor)

Children

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Collaborators

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Publications

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Vasavda C, Semenza ER, Liew J, et al. (2022) Biliverdin reductase bridges focal adhesion kinase to Src to modulate synaptic signaling. Science Signaling. 15: eabh3066
Rao F, Cha J, Xu J, et al. (2020) Inositol Pyrophosphates Mediate the DNA-PK/ATM-p53 Cell Death Pathway by Regulating CK2 Phosphorylation of Tti1/Tel2. Molecular Cell. 79: 702
Paul BD, Vasavda C, Kothari R, et al. (2020) The role of bilirubin and heme metabolism in neuronal stress signaling The Faseb Journal. 34: 1-1
Vasavda C, Kothari R, Malla AP, et al. (2019) Bilirubin Links Heme Metabolism to Neuroprotection by Scavenging Superoxide. Cell Chemical Biology
Long J, Tokhunts R, Old WM, et al. (2015) Identification of a family of fatty-acid-speciated sonic hedgehog proteins, whose members display differential biological properties. Cell Reports. 10: 1280-7
Rao F, Cha J, Xu J, et al. (2014) Inositol pyrophosphates mediate the DNA-PK/ATM-p53 cell death pathway by regulating CK2 phosphorylation of Tti1/Tel2. Molecular Cell. 54: 119-32
Rodriguez-Blanco J, Schilling NS, Tokhunts R, et al. (2013) The hedgehog processing pathway is required for NSCLC growth and survival. Oncogene. 32: 2335-45
Fei DL, Sanchez-Mejias A, Wang Z, et al. (2012) Hedgehog signaling regulates bladder cancer growth and tumorigenicity. Cancer Research. 72: 4449-58
Singh S, Wang Z, Liang Fei D, et al. (2011) Hedgehog-producing cancer cells respond to and require autocrine Hedgehog activity. Cancer Research. 71: 4454-63
Xiao C, Ogle SA, Schumacher MA, et al. (2010) Hedgehog signaling regulates E-cadherin expression for the maintenance of the actin cytoskeleton and tight junctions. American Journal of Physiology. Gastrointestinal and Liver Physiology. 299: G1252-65
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