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Sign in to add mentor| Alexandra C. Newton | grad student | 2006-2012 | UCSD (Chemistry Tree) | |
| (Signaling by PHLPP1 and PKC alpha: Function and specificity.) | ||||
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Publications
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| O'Neill AK, Kindberg AA, Niethamer TK, et al. (2016) Unidirectional Eph/ephrin signaling creates a cortical actomyosin differential to drive cell segregation. The Journal of Cell Biology. 215: 217-229 |
| O'Neill AK, Niederst MJ, Newton AC. (2013) Suppression of survival signalling pathways by the phosphatase PHLPP. The Febs Journal. 280: 572-83 |
| Abrahamsen H, O'Neill AK, Kannan N, et al. (2012) Peptidyl-prolyl isomerase Pin1 controls down-regulation of conventional protein kinase C isozymes. The Journal of Biological Chemistry. 287: 13262-78 |
| O'Neill AK, Gallegos LL, Justilien V, et al. (2011) Protein kinase Cα promotes cell migration through a PDZ-dependent interaction with its novel substrate discs large homolog 1 (DLG1). The Journal of Biological Chemistry. 286: 43559-68 |
| Chen M, Pratt CP, Zeeman ME, et al. (2011) Identification of PHLPP1 as a tumor suppressor reveals the role of feedback activation in PTEN-mutant prostate cancer progression. Cancer Cell. 20: 173-86 |
| Patterson SJ, Han JM, Garcia R, et al. (2011) Cutting edge: PHLPP regulates the development, function, and molecular signaling pathways of regulatory T cells. Journal of Immunology (Baltimore, Md. : 1950). 186: 5533-7 |
| Xu Q, Fitzsimmons B, Steinauer J, et al. (2011) Spinal phosphinositide 3-kinase-Akt-mammalian target of rapamycin signaling cascades in inflammation-induced hyperalgesia. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 2113-24 |
| Chen M, Pratt CP, Zeeman ME, et al. (2011) Abstract 2405: Identification of PHLPP as a tumour suppressor reveals the role of pathway feedback compensation in PTEN-mutant prostate cancer progression Cancer Research. 71: 2405-2405 |
| Masubuchi S, Gao T, O'Neill A, et al. (2010) Protein phosphatase PHLPP1 controls the light-induced resetting of the circadian clock. Proceedings of the National Academy of Sciences of the United States of America. 107: 1642-7 |
| Patterson S, Garcia R, O'Neill A, et al. (2010) PHLPP Regulates the Development, Function and Molecular Signaling Pathways of T Regulatory Cells Clinical Immunology. 135: S6 |