Ashraf brik

Affiliations: 
Chemistry Technion - Israel Institute of Technology, Haifa, Haifa District, Israel 
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"Ashraf brik"
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Muhammad Jbara grad student
Muhammad Jbara grad student 2015-2019 Technion
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Hasan M, Panda D, Mann G, et al. (2023) De novo Semi-synthetic Platform for Monitoring Protein degradation in Live Cells. Chembiochem : a European Journal of Chemical Biology. e202300731
Lemma B, Zhang D, Vamisetti GB, et al. (2023) Mechanism of selective recognition of Lys48-linked polyubiquitin by macrocyclic peptide inhibitors of proteasomal degradation. Nature Communications. 14: 7212
Kriegesmann J, Brik A. (2023) Synthesis of ubiquitinated proteins for biochemical and functional analysis. Chemical Science. 14: 10025-10040
Parisis N, Dans PD, Jbara M, et al. (2023) Histone H3 serine-57 is a CHK1 substrate whose phosphorylation affects DNA repair. Nature Communications. 14: 5104
Saha A, Suga H, Brik A. (2023) Combining Chemical Protein Synthesis and Random Nonstandard Peptides Integrated Discovery for Modulating Biological Processes. Accounts of Chemical Research
Vamisetti GB, Saha A, Huang YJ, et al. (2022) Selective macrocyclic peptide modulators of Lys63-linked ubiquitin chains disrupt DNA damage repair. Nature Communications. 13: 6174
Mann G, Sulkshane P, Sadhu P, et al. (2022) Antibody for Serine 65 Phosphorylated Ubiquitin Identifies PLK1-Mediated Phosphorylation of Mitotic Proteins and APC1. Molecules (Basel, Switzerland). 27
Mann G, Sadhu P, Brik A. (2022) Synthetic Proteins behind the Plasma Barrier: Molecular Spies. Accounts of Chemical Research. 55: 2055-2067
Vanjari R, Panda D, Mandal S, et al. (2022) Gold(I)-Mediated Rapid Cyclization of Propargylated Peptides via Imine Formation. Journal of the American Chemical Society. 144: 4966-4976
Mann G, Sadhu P, Brik A. (2022) Multiplexed Delivery of Synthetic (Un)Conjugatable Ubiquitin and SUMO2 Enables Simultaneous Monitoring of Their Localization and Function in Live Cells. Chembiochem : a European Journal of Chemical Biology. e202200122
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