Juan Carlos Lacal
Affiliations: | Instituto de Investigaciones Biomédicas "Alberto Sols" |
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Publications
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Zimmerman T, Lacal JC, Ibrahim SA. (2019) Choline Kinase Emerges as a Promising Drug Target in Gram-Positive Bacteria. Frontiers in Microbiology. 6: 2146 |
Valdés-Mora F, Locke WJ, Bandrés E, et al. (2017) Clinical relevance of the transcriptional signature regulated by CDC42 in colorectal cancer. Oncotarget. 8: 26755-26770 |
Marien E, Meister M, Muley T, et al. (2016) Phospholipid profiling identifies acyl chain elongation as a ubiquitous trait and potential target for the treatment of lung squamous cell carcinoma. Oncotarget |
Lacal JC, Andera L. (2016) Choline kinase inhibitors synergize with TRAIL in the treatment of colorectal tumors and overcomes TRAIL resistance Cancer Translational Medicine. 2: 163 |
Estévez-Braun A, Ravelo AG, Pérez-Sacau E, et al. (2015) A new family of choline kinase inhibitors with antiproliferative and antitumor activity derived from natural products. Clinical & Translational Oncology. 17: 74-84 |
Zimmerman T, Moneriz C, Diez A, et al. (2013) Antiplasmodial activity and mechanism of action of RSM-932A, a promising synergistic inhibitor of Plasmodium falciparum choline kinase. Antimicrobial Agents and Chemotherapy. 57: 5878-88 |
Cueva Adl, Molina ARd, Álvarez-Ayerza N, et al. (2013) Combined 5-FU and ChoKα Inhibitors as a New Alternative Therapy of Colorectal Cancer: Evidence in Human Tumor-Derived Cell Lines and Mouse Xenografts Plos One. 8 |
Casado-Vela J, Lacal JC, Elortza F. (2013) Protein chimerism: novel source of protein diversity in humans adds complexity to bottom-up proteomics. Proteomics. 13: 5-11 |
Pintzas A, Zhivotovsky B, Workman P, et al. (2012) Sensitization of (colon) cancer cells to death receptor related therapies: a report from the FP6-ONCODEATH research consortium. Cancer Biology & Therapy. 13: 458-66 |
Gallego-Ortega D, Pulgar TGd, Valdés-Mora F, et al. (2011) Involvement of human choline kinase alpha and beta in carcinogenesis: a different role in lipid metabolism and biological functions. Advances in Enzyme Regulation. 51: 183-194 |