Robert F. Spurney

Affiliations: 
Duke University, Durham, NC 
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"Robert Spurney"
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Wang L, Chang JH, Buckley AF, et al. (2019) Knockout of TRPC6 promotes insulin resistance and exacerbates glomerular injury in Akita mice. Kidney International. 95: 321-332
Wang L, Buckley AF, Spurney RF. (2018) Regulation of cofilin phosphorylation in glomerular podocytes by testis specific kinase 1 (TESK1). Scientific Reports. 8: 12286
Hall G, Lane BM, Khan K, et al. (2018) The Human FSGS-Causing R431C Mutation Induces Dysregulated PI3K/AKT/mTOR/Rac1 Signaling in Podocytes. Journal of the American Society of Nephrology : Jasn
Hall G, Spurney RF. (2017) Losing their footing: Rac1 signaling causes podocyte detachment and FSGS. Kidney International. 92: 283-285
Wang L, Jirka G, Rosenberg PB, et al. (2015) Gq signaling causes glomerular injury by activating TRPC6. The Journal of Clinical Investigation. 125: 1913-26
Hall G, Rowell J, Farinelli F, et al. (2014) Phosphodiesterase 5 inhibition ameliorates angiontensin II-induced podocyte dysmotility via the protein kinase G-mediated downregulation of TRPC6 activity. American Journal of Physiology. Renal Physiology. 306: F1442-50
Wang X, Liao S, Nelson ER, et al. (2012) The cytoskeletal regulatory scaffold protein GIT2 modulates mesenchymal stem cell differentiation and osteoblastogenesis. Biochemical and Biophysical Research Communications. 425: 407-12
Zhang JD, Patel MB, Song YS, et al. (2012) A novel role for type 1 angiotensin receptors on T lymphocytes to limit target organ damage in hypertension. Circulation Research. 110: 1604-17
Wang L, Ellis MJ, Gomez JA, et al. (2012) Mechanisms of the proteinuria induced by Rho GTPases. Kidney International. 81: 1075-85
Wang L, Chang JH, Paik SY, et al. (2011) Calcineurin (CN) activation promotes apoptosis of glomerular podocytes both in vitro and in vivo. Molecular Endocrinology (Baltimore, Md.). 25: 1376-86
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