Smit Kour

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2016-2020 University of Nebraska Medical Center, Omaha, NE, United States 
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"Smit Kour"
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Napoleon JV, Sagar S, Kubica SP, et al. (2022) Small-molecule IKKβ activation modulator (IKAM) targets MAP3K1 and inhibits pancreatic tumor growth. Proceedings of the National Academy of Sciences of the United States of America. 119: e2115071119
Kour S, Rana S, Kubica SP, et al. (2022) Spirocyclic dimer SpiD7 activates the unfolded protein response to selectively inhibit growth and induce apoptosis of cancer cells. The Journal of Biological Chemistry. 101890
Rana S, Kour S, Kizhake S, et al. (2022) Dimers of isatin derived α-methylene-γ-butyrolactone as potent anti-cancer agents. Bioorganic & Medicinal Chemistry Letters. 65: 128713
Robb CM, Kour S, Contreras JI, et al. (2020) Correction: Characterization of CDK(5) inhibitor, 20-223 (aka CP668863) for colorectal cancer therapy. Oncotarget. 11: 2462-2463
Rana S, Kour S, Sonawane YA, et al. (2020) Symbiotic Prodrugs (SymProDs) Dual Targeting of NFkappaB and CDK. Chemical Biology & Drug Design
Kour S, Rana S, Contreras JI, et al. (2019) CDK5 Inhibitor Downregulates Mcl-1 and Sensitizes Pancreatic Cancer Cell Lines to Navitoclax. Molecular Pharmacology. 96: 419-429
Rana S, Bendjennat M, Kour S, et al. (2019) Selective degradation of CDK6 by a palbociclib based PROTAC. Bioorganic & Medicinal Chemistry Letters
Contreras JI, Robb CM, King HM, et al. (2018) Chemical Genetic Screens Identify Kinase Inhibitor Combinations that Target Anti-Apoptotic Proteins for Cancer Therapy. Acs Chemical Biology
Robb CM, Kour S, Contreras JI, et al. (2018) Characterization of CDK(5) inhibitor, 20-223 (aka CP668863) for colorectal cancer therapy. Oncotarget. 9: 5216-5232
Robb CM, Contreras JI, Kour S, et al. (2017) Chemically induced degradation of CDK9 by a proteolysis targeting chimera (PROTAC). Chemical Communications (Cambridge, England)
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