Alex Almasan, PhD
Affiliations: | 1995- | Cancer Biology | The Cleveland Clinic, Cleveland, OH, United States |
Area:
apoptosis, autophagy, DNA repairWebsite:
http://www.lerner.ccf.org/cancerbio/almasan/Google:
"https://scholar.google.com/citations?user=T25Wih4AAAAJ&hl=en&oi=ao"Parents
Sign in to add mentor| Nawin C. Mishra | grad student | 1984-1989 | University of South Carolina |
| Geoffrey M. Wahl | post-doc | 1989-1994 | Slak Institute |
Children
Sign in to add trainee| Sayer Alharbi | grad student | Cleveland State University | |
| Turkeyah Alswillah | grad student | Cleveland State University | |
| Payel Chatterjee | grad student | Kent State University, FRCRC (Neurotree) | |
| Gaurav Choudhary | grad student | Case Western (Chemistry Tree) | |
| Meredith Crosby | grad student | Case Western Reserve University, Yale University | |
| Erica L. DuPree | grad student | Cleveland State University | |
| Marcela Oancea | grad student | Cleveland State, Roche | |
| Dragos Plesca | grad student | Kent State University, Carolinas Medical Center & Levine Cancer Institute | |
| Arishya Sharma | grad student | Cleveland State University (Chemistry Tree) | |
| Suparna Mazumder | post-doc | Cleveland Clinic | |
| Chen, Quan | post-doc | Nankai University | |
| Kamini Sngh | post-doc | Pune University, MSKCC |
BETA: Related publications
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Publications
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| Sharma A, Almasan A. (2020) USP14 Regulates DNA Damage Response and Is a Target for Radiosensitization in Non-Small Cell Lung Cancer. International Journal of Molecular Sciences. 21 |
| Zhang F, Lou L, Peng B, et al. (2020) Nudix hydrolase NUDT16 regulates 53BP1 protein by reversing 53BP1 ADP-ribosylation. Cancer Research |
| Kapoor I, Li Y, Sharma A, et al. (2019) Resistance to BTK inhibition by ibrutinib can be overcome by preventing FOXO3a nuclear export and PI3K/AKT activation in B-cell lymphoid malignancies. Cell Death & Disease. 10: 924 |
| Sharma A, Alswillah T, Kapoor I, et al. (2019) USP14 is a deubiquitinase for Ku70 and critical determinant of non-homologous end joining repair in autophagy and PTEN-deficient cells. Nucleic Acids Research |
| La Belle Flynn A, Calhoun BC, Sharma A, et al. (2019) Autophagy inhibition elicits emergence from metastatic dormancy by inducing and stabilizing Pfkfb3 expression. Nature Communications. 10: 3668 |
| Qian M, Almasan A, Gürkan-Çavusoglu E. (2019) Abstract 686: Quantitative analysis of the role of homologous recombination in response to radiotherapy for prostate cancer Cancer Research |
| Sharma A, Almasan A. (2018) Autophagy as a mechanism of Apo2L/TRAIL resistance. Cancer Biology & Therapy. 1-8 |
| Sharma A, Alswillah T, Singh K, et al. (2018) USP14 regulates DNA damage repair by targeting RNF168-dependent ubiquitination. Autophagy |
| Li Y, Kapoor I, Zhu H, et al. (2018) Abstract 2857: PI3K/AKT activation in de novo and acquired resistance to ibrutinib in lymphoid malignancies Cancer Research. 78: 2857-2857 |
| Zhu H, Almasan A. (2017) Development of venetoclax for therapy of lymphoid malignancies. Drug Design, Development and Therapy. 11: 685-694 |