Xandra Owens Breakefield

Affiliations: 
Harvard Medical School/ MGH, Boston, MA, United States 
Area:
Neurogenetics, Gene Therapy
Website:
http://www.massgeneral.org/breakefieldlab/
Google:
"Xandra Breakefield"
Mean distance: 14.32 (cluster 11)
 
SNBCP
Cross-listing: Cell & Gene Therapy Tree

Parents

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Marshall Nirenberg post-doc 1973-1974

Children

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Jeremiah M. Scharf research assistant 1993-1994 MGH
Casey A. Maguire post-doc Harvard Medical School/ MGH (Cell & Gene Therapy Tree)
D. Cristopher Bragg post-doc 2000-2004 Harvard Medical School
Jeremy C. Petravicz research scientist MIT
BETA: Related publications

Publications

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Maalouf KE, Vaine CA, Frederick DM, et al. (2023) Tracking human neurologic disease status in mouse brain/plasma using reporter-tagged, EV-associated biomarkers. Molecular Therapy : the Journal of the American Society of Gene Therapy
Prabhakar S, Beauchamp RL, Cheah PS, et al. (2022) Gene replacement therapy in a schwannoma mouse model of neurofibromatosis type 2. Molecular Therapy. Methods & Clinical Development. 26: 169-180
Cheah PS, Prabhakar S, Yellen D, et al. (2021) Gene therapy for tuberous sclerosis complex type 2 in a mouse model by delivery of AAV9 encoding a condensed form of tuberin. Science Advances. 7
Al Ali J, Vaine CA, Shah S, et al. (2020) TAF1 Transcripts and Neurofilament Light Chain as Biomarkers for X-Linked Dystonia-Parkinsonism. Movement Disorders : Official Journal of the Movement Disorder Society
Abels ER, Maas SLN, Tai E, et al. (2020) GlioM&M: Web-based tool for studying circulating and infiltrating monocytes and macrophages in glioma. Scientific Reports. 10: 9898
Cruz L, György B, Cheah PS, et al. (2020) Mutant Allele-Specific CRISPR Disruption in DYT1 Dystonia Fibroblasts Restores Cell Function. Molecular Therapy. Nucleic Acids. 21: 1-12
O'Brien K, Breyne K, Ughetto S, et al. (2020) RNA delivery by extracellular vesicles in mammalian cells and its applications. Nature Reviews. Molecular Cell Biology
Maas SLN, Abels ER, Van De Haar LL, et al. (2020) Glioblastoma hijacks microglial gene expression to support tumor growth. Journal of Neuroinflammation. 17: 120
Lucero R, Zappulli V, Sammarco A, et al. (2020) Glioma-Derived miRNA-Containing Extracellular Vesicles Induce Angiogenesis by Reprogramming Brain Endothelial Cells. Cell Reports. 30: 2065-2074.e4
Yekula A, Minciacchi VR, Morello M, et al. (2020) Large and small extracellular vesicles released by glioma cells and . Journal of Extracellular Vesicles. 9: 1689784
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