Tak Wah Mak, Ph.D.

Affiliations: 
Immunology University of Toronto, Toronto, ON, Canada 
Website:
https://www.uhnresearch.ca/researcher/tak-w-mak
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"Tak Wah Mak"
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Parents

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Ernest McCulloch post-doc (Cell Biology Tree)
Howard M. Temin post-doc
James Edgar Till research scientist (Neurotree)
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Publications

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Man CH, Lam W, Dang CC, et al. (2023) Inhibition of PLK4 remodels histone methylation and activates immune response via cGAS-STING pathway in TP53 mutated AML. Blood
Miyachi Y, Nishio M, Otani J, et al. (2021) TAZ inhibits acinar cell differentiation but promotes immature ductal cell proliferation in adult mouse salivary glands. Genes to Cells : Devoted to Molecular & Cellular Mechanisms
Maehama T, Nishio M, Otani J, et al. (2020) The Role of Hippo-YAP Signaling in Squamous Cell Carcinomas. Cancer Science
Kato W, Nishio M, To Y, et al. (2019) MOB1 regulates thymocyte egress and T cell survival in mice in a YAP1-independent manner. Genes to Cells : Devoted to Molecular & Cellular Mechanisms
Nishio M, Miyachi Y, Otani J, et al. (2019) Hippo pathway controls cell adhesion and context-dependent cell competition to influence skin engraftment efficiency. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. fj201802005R
Goto H, Nishio M, To Y, et al. (2018) Loss ofin mice results in chondrodysplasia due to YAP1/TAZ-TEADs-dependent repression of SOX9. Development (Cambridge, England)
Liu CJ, Tsai CY, Chiang SH, et al. (2017) Triggering receptor expressed on myeloid cells-1 (TREM-1) deficiency augments BAFF production to promote lupus progression. Journal of Autoimmunity
Chng SH, Kundu P, Dominguez-Brauer C, et al. (2016) Ablating the aryl hydrocarbon receptor (AhR) in CD11c+ cells perturbs intestinal epithelium development and intestinal immunity. Scientific Reports. 6: 23820
Chang YL, Chen TH, Wu YH, et al. (2014) A novel TLR2-triggered signalling crosstalk synergistically intensifies TNF-mediated IL-6 induction. Journal of Cellular and Molecular Medicine. 18: 1344-57
Sasaki M, Knobbe CB, Itsumi M, et al. (2012) D-2-hydroxyglutarate produced by mutant IDH1 perturbs collagen maturation and basement membrane function. Genes & Development. 26: 2038-49
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