Ioanna Ledaki
Affiliations: | 2008-2013 | University of Oxford, Oxford, United Kingdom |
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"Ioanna Ledaki"
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Publications
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Louphrasitthiphol P, Ledaki I, Chauhan J, et al. (2019) MITF controls the TCA cycle to modulate the melanoma hypoxia response. Pigment Cell & Melanoma Research |
Lisboa da Motta L, Ledaki I, Haider S, et al. (2018) PO-276 Histone acetylation readers BET in hypoxia adaptation in triple negative breast cancer (TNBC) Esmo Open. 3: A335 |
da Motta LL, Ledaki I, Purshouse K, et al. (2016) The BET inhibitor JQ1 selectively impairs tumour response to hypoxia and downregulates CA9 and angiogenesis in triple negative breast cancer. Oncogene |
McIntyre A, Hulikova A, Ledaki I, et al. (2016) Disrupting hypoxia-induced bicarbonate transport acidifies tumor cells and suppresses tumor growth. Cancer Research |
Ledaki I, McIntyre A, Wigfield S, et al. (2015) Carbonic anhydrase IX induction defines a heterogeneous cancer cell response to hypoxia and mediates stem cell-like properties and sensitivity to HDAC inhibition. Oncotarget. 6: 19413-27 |
McIntyre A, Hulikova A, Ledaki I, et al. (2013) Abstract 4053: Hypoxic trans-activation of sodium dependent bicarbonate co-transporters regulates pH in 3D spheroids and promotes growth. Cancer Research. 73: 4053-4053 |
McIntyre A, Patiar S, Wigfield S, et al. (2012) Carbonic anhydrase IX promotes tumor growth and necrosis in vivo and inhibition enhances anti-VEGF therapy. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 18: 3100-11 |
Sivridis E, Koukourakis MI, Zois CE, et al. (2010) LC3A-positive light microscopy detected patterns of autophagy and prognosis in operable breast carcinomas. The American Journal of Pathology. 176: 2477-89 |
Yang J, Ledaki I, Turley H, et al. (2009) Role of hypoxia-inducible factors in epigenetic regulation via histone demethylases. Annals of the New York Academy of Sciences. 1177: 185-97 |