Helen Knowles

Affiliations: 
University of Oxford, Oxford, United Kingdom 
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"Helen Knowles"
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Knowles HJ. (2020) Distinct roles for the hypoxia-inducible transcription factors HIF-1α and HIF-2α in human osteoclast formation and function. Scientific Reports. 10: 21072
Knowles HJ. (2017) Multiple Roles of Angiopoietin-Like 4 in Osteolytic Disease. Frontiers in Endocrinology. 8: 80
Hulley PA, Bishop T, Vernet A, et al. (2017) Hypoxia-Inducible Factor 1-alpha does not regulate osteoclastogenesis but enhances bone resorption activity via prolyl-4-hydroxylase 2. The Journal of Pathology
Knowles HJ. (2017) Hypoxia-Induced Fibroblast Growth Factor 11 Stimulates Osteoclast-Mediated Resorption of Bone. Calcified Tissue International. 100: 382-391
Taylor RM, Kashima TG, Knowles HJ, et al. (2012) VEGF, FLT3 ligand, PlGF and HGF can substitute for M-CSF to induce human osteoclast formation: implications for giant cell tumour pathobiology. Laboratory Investigation; a Journal of Technical Methods and Pathology. 92: 1398-406
Taylor R, Knowles HJ, Athanasou NA. (2011) Ewing sarcoma cells express RANKL and support osteoclastogenesis. The Journal of Pathology. 225: 195-202
Knowles HJ, Cleton-Jansen AM, Korsching E, et al. (2010) Hypoxia-inducible factor regulates osteoclast-mediated bone resorption: role of angiopoietin-like 4. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 24: 4648-59
Knowles HJ, Schaefer KL, Dirksen U, et al. (2010) Hypoxia and hypoglycaemia in Ewing's sarcoma and osteosarcoma: regulation and phenotypic effects of Hypoxia-Inducible Factor. Bmc Cancer. 10: 372
Benson RT, McDonnell SM, Knowles HJ, et al. (2010) Tendinopathy and tears of the rotator cuff are associated with hypoxia and apoptosis. The Journal of Bone and Joint Surgery. British Volume. 92: 448-53
Knowles H, Cleton-Jansen A, Korsching E, et al. (2010) Hypoxia-Inducible Factor (HIF) regulates Osteoclast-Mediated Bone Resorption via Angiopoietin-like 4 (ANGPTL4) Bone. 46
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