Kathy Fange Liu, Ph.D.

Affiliations: 
2008-2013 Department of Chemistry Georgia State University, Atlanta, GA, United States 
 2013-2017 Department of Chemistry University of Chicago, Chicago, IL 
 2018- Department of Biochemistry and Biophysics University of Pennsylvania, Philadelphia, PA, United States 
Area:
RNA enzymology, Sex-specific RNA biology, Protein structure-function
Website:
https://www.med.upenn.edu/kathyliulab/
Google:
"Fange Liu"
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Children

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Justin Curtiss grad student Penn
Heidi Elashal grad student Penn
Ellen Lavorando grad student Penn
Michael Owens grad student Penn
Amber Yanas grad student Penn
Robert Jordan Ontiveros grad student 2018-2022 Penn
Julian Stoute grad student 2018-2023 Penn
Yulia Gonskikh post-doc Penn
Yulia Gonskikh post-doc Penn
Maria Sarai Mendoza post-doc Penn
Hui Shen post-doc Penn
Xiaoyu Wei research scientist 2022- Penn
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Publications

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Yanas A, Shweta H, Owens MC, et al. (2023) DDX3X and DDX3Y constitutively form nano-sized RNA-protein clusters that foster enzymatic activity. Biorxiv : the Preprint Server For Biology
Owens MC, Shen H, Yanas A, et al. (2023) Mutant forms of DDX3X with diminished catalysis form hollow condensates that exhibit sex-specific regulation. Biorxiv : the Preprint Server For Biology
Maldonado López AM, Ko EK, Huang S, et al. (2023) Mettl3-catalyzed mA regulates histone modifier and modification expression in self-renewing somatic tissue. Science Advances. 9: eadg5234
Chen AY, Owens MC, Liu KF. (2023) Coordination of RNA modifications in the brain and beyond. Molecular Psychiatry
Gonskikh Y, Stoute J, Shen H, et al. (2023) Noncatalytic regulation of 18 rRNA methyltransferase DIMT1 in acute myeloid leukemia. Genes & Development
Owens MC, Liu KF. (2022) TRIBE-STAMP reveals new insights into the functions of RNA binding proteins. Genes & Development. 36: 954-955
Basavappa MG, Ferretti M, Dittmar M, et al. (2022) The lncRNA ALPHA specifically targets chikungunya virus to control infection. Molecular Cell
Perlegos AE, Shields EJ, Shen H, et al. (2022) Mettl3-dependent mA modification attenuates the brain stress response in Drosophila. Nature Communications. 13: 5387
Santoleri D, Lim HW, Emmett MJ, et al. (2022) Global-run on sequencing identifies as an Akt-dependent long noncoding RNA involved in insulin sensitivity. Iscience. 25: 104410
Shen H, Yanas A, Owens MC, et al. (2022) Sexually dimorphic RNA helicases DDX3X and DDX3Y differentially regulate RNA metabolism through phase separation. Molecular Cell
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