Isabel Pires

Affiliations: 
University of Manchester (UK) 
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"Isabel Pires"
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Poujade FA, Mannion A, Brittain N, et al. (2018) WSB-1 regulates the metastatic potential of hormone receptor negative breast cancer. British Journal of Cancer
Pefani DE, Latusek R, Pires I, et al. (2015) RASSF1A-LATS1 signalling stabilizes replication forks by restricting CDK2-mediated phosphorylation of BRCA2. Nature Cell Biology. 17: 531
Pefani DE, Latusek R, Pires I, et al. (2014) RASSF1A-LATS1 signalling stabilizes replication forks by restricting CDK2-mediated phosphorylation of BRCA2 Nature Cell Biology. 16: 962-971
Pires IM, Blokland NJ, Broos AW, et al. (2014) HIF-1α-independent hypoxia-induced rapid PTK6 stabilization is associated with increased motility and invasion. Cancer Biology & Therapy. 15: 1350-7
Scrace S, O'Neill E, Hammond EM, et al. (2014) Use of the xCELLigence system for real-time analysis of changes in cellular motility and adhesion in physiological conditions. Methods in Molecular Biology (Clifton, N.J.). 1046: 295-306
Olcina MM, Foskolou IP, Anbalagan S, et al. (2013) Replication stress and chromatin context link ATM activation to a role in DNA replication Molecular Cell. 52: 758-766
Cazares-Körner C, Pires IM, Swallow ID, et al. (2013) CH-01 is a hypoxia-activated prodrug that sensitizes cells to hypoxia/reoxygenation through inhibition of Chk1 and Aurora A. Acs Chemical Biology. 8: 1451-9
Anbalagan S, Pires IM, Blick C, et al. (2012) Radiosensitization of renal cell carcinoma in vitro through the induction of autophagy. Radiotherapy and Oncology : Journal of the European Society For Therapeutic Radiology and Oncology. 103: 388-93
Pires IM, Bencokova Z, McGurk C, et al. (2011) Exposure to acute hypoxia induces a transient DNA damage response which includes Chk1 and TLK1. Cell Cycle (Georgetown, Tex.). 9: 2502-7
Chan N, Pires IM, Bencokova Z, et al. (2010) Contextual synthetic lethality of cancer cell kill based on the tumor microenvironment. Cancer Research. 70: 8045-54
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