Irini Evnouchidou

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2006-2010 NCSR Demokritos 
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"Irini Evnouchidou"
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Publications

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Maben Z, Arya R, Rane D, et al. (2019) Discovery of Selective Inhibitors of Endoplasmic Reticulum Aminopeptidase 1. Journal of Medicinal Chemistry
Weimershaus M, Evnouchidou I, Li L, et al. (2019) Trimming of MHC Class I Ligands by ERAP Aminopeptidases. Methods in Molecular Biology (Clifton, N.J.). 1988: 31-43
Lawand M, Evnouchidou I, Baranek T, et al. (2018) Impact of the TAP-like transporter in antigen presentation and phagosome maturation. Molecular Immunology
Chen H, Li L, Weimershaus M, et al. (2016) ERAP1-ERAP2 dimers trim MHC I-bound precursor peptides; implications for understanding peptide editing. Scientific Reports. 6: 28902
Seregin SS, Rastall DP, Evnouchidou I, et al. (2013) Endoplasmic reticulum aminopeptidase-1 alleles associated with increased risk of ankylosing spondylitis reduce HLA-B27 mediated presentation of multiple antigens. Autoimmunity. 46: 497-508
Evnouchidou I, Birtley J, Seregin S, et al. (2012) A common single nucleotide polymorphism in endoplasmic reticulum aminopeptidase 2 induces a specificity switch that leads to altered antigen processing. Journal of Immunology (Baltimore, Md. : 1950). 189: 2383-92
Kim S, Lee S, Shin J, et al. (2011) Human cytomegalovirus microRNA miR-US4-1 inhibits CD8(+) T cell responses by targeting the aminopeptidase ERAP1. Nature Immunology. 12: 984-91
Nguyen TT, Chang SC, Evnouchidou I, et al. (2011) Structural basis for antigenic peptide precursor processing by the endoplasmic reticulum aminopeptidase ERAP1. Nature Structural & Molecular Biology. 18: 604-13
Zervoudi E, Papakyriakou A, Georgiadou D, et al. (2011) Probing the S1 specificity pocket of the aminopeptidases that generate antigenic peptides. The Biochemical Journal. 435: 411-20
Evnouchidou I, Kamal RP, Seregin SS, et al. (2011) Cutting Edge: Coding single nucleotide polymorphisms of endoplasmic reticulum aminopeptidase 1 can affect antigenic peptide generation in vitro by influencing basic enzymatic properties of the enzyme. Journal of Immunology (Baltimore, Md. : 1950). 186: 1909-13
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