Nickolay V. Kukekov

Affiliations: 
2005 Columbia University, New York, NY 
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"Nickolay Kukekov"
Mean distance: 16.47 (cluster 11)
 
SNBCP

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Lloyd Greene grad student 2005 Columbia
 (Role of the molecular scaffold POSH in activation of the JNK pathway.)
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Wilhelm M, Kukekov NV, Schmit TL, et al. (2012) Sh3rf2/POSHER protein promotes cell survival by ring-mediated proteasomal degradation of the c-Jun N-terminal kinase scaffold POSH (Plenty of SH3s) protein. The Journal of Biological Chemistry. 287: 2247-56
Wilhelm M, Kukekov NV, Xu Z, et al. (2007) Identification of POSH2, a novel homologue of the c-Jun N-terminal kinase scaffold protein POSH. Developmental Neuroscience. 29: 355-62
Wilhelm M, Xu Z, Kukekov NV, et al. (2007) Proapoptotic Nix activates the JNK pathway by interacting with POSH and mediates death in a Parkinson disease model. The Journal of Biological Chemistry. 282: 1288-95
Kukekov NV, Xu Z, Greene LA. (2006) Direct interaction of the molecular scaffolds POSH and JIP is required for apoptotic activation of JNKs. The Journal of Biological Chemistry. 281: 15517-24
Xu Z, Kukekov NV, Greene LA. (2005) Regulation of apoptotic c-Jun N-terminal kinase signaling by a stabilization-based feed-forward loop. Molecular and Cellular Biology. 25: 9949-59
Wilhelm M, Gire S, Xu Z, et al. (2005) POSH REGULATES JNK ACTIVATION BY THE BH3-ONLY PROTEIN NIX. Critical Care Medicine. 33: A16
Wilhelm M, Vannucci SJ, Kukekov NV, et al. (2004) A NOVEL POSH HOMOLOGUE AND ITS ROLE IN NEURONAL APOPTOSIS Critical Care Medicine. 32: A98
Xu Z, Kukekov NV, Greene LA. (2003) POSH acts as a scaffold for a multiprotein complex that mediates JNK activation in apoptosis. The Embo Journal. 22: 252-61
Xu Z, Maroney AC, Dobrzanski P, et al. (2001) The MLK family mediates c-Jun N-terminal kinase activation in neuronal apoptosis. Molecular and Cellular Biology. 21: 4713-24
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